Platz-Christensen J J, Larsson P G, Sundström E, Bondeson L
Department of Obstetrics and Gynecology, Central Hospital, Skövde, Sweden.
Am J Obstet Gynecol. 1989 Jan;160(1):132-3. doi: 10.1016/0002-9378(89)90104-x.
In a prospective study of 145 women, bacterial vaginosis was clinically diagnosed in 46 women. Compared with clinical diagnosis of bacterial vaginosis, detection of so-called clue cells in Papanicolaou smears showed a sensitivity of 90% and a specificity of 97%. The positive and negative predictive values were 94% and 95%, respectively. The study results indicate that demonstration of clue cells in Papanicolaou smears is a useful method for identification of women with probable bacterial vaginosis. This provides a basis for the use of archival material in retrospective studies with regard to possible links between bacterial vaginosis and development of cervical cancer.
在一项针对145名女性的前瞻性研究中，46名女性被临床诊断为细菌性阴道病。与细菌性阴道病的临床诊断相比，巴氏涂片检查中所谓线索细胞的检测显示敏感性为90%，特异性为97%。阳性和阴性预测值分别为94%和95%。研究结果表明，巴氏涂片中线索细胞的显示是识别可能患有细菌性阴道病女性的一种有用方法。这为在回顾性研究中使用存档材料以探讨细菌性阴道病与宫颈癌发生之间可能的联系提供了依据。
