淋巴瘤中长链非编码 RNA 的鉴定。
Long noncoding RNA identification in lymphoma.
机构信息
Department of Medicine, Nantong University, Nantong, Jiangsu 226001, PR China.
Department of Human Anatomy, Nantong University, Nantong, Jiangsu 226001, PR China.
出版信息
Future Oncol. 2017 Nov;13(27):2479-2487. doi: 10.2217/fon-2017-0230. Epub 2017 Nov 10.
It has been found that long noncoding RNA (lncRNA) are abnormally expressed in lymphoma and play an important role in its pathogenesis. Through the detection and analysis of lncRNA, it was found that lncRNA could be used as an excellent biomarker for the diagnosis and prognosis of cancer. In lymphoma, abnormal lncRNA expression is associated with the patient's clinical characteristics, it can be used to determine the prognosis of the patient and serve as a therapeutic target in the disease.
现已发现，长链非编码 RNA（lncRNA）在淋巴瘤中异常表达，并在其发病机制中发挥重要作用。通过对 lncRNA 的检测和分析，发现 lncRNA 可用作癌症诊断和预后的优秀生物标志物。在淋巴瘤中，异常的 lncRNA 表达与患者的临床特征相关，可用于判断患者的预后，并作为疾病的治疗靶点。
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