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从进口食品中分离出的具有多重抗生素耐药性的环丙沙星耐药菌株的基因组序列草图

Draft Genome Sequences of Ciprofloxacin-Resistant Strains with Multiple-Antibiotic Resistance, Isolated from Imported Foods.

作者信息

Khan Ashraf A, Khajanchi Bijay K, Khan Sana A, Elkins Christopher A, Foley Steven L

机构信息

U.S. Food and Drug Administration, National Center for Toxicological Research, Jefferson, Arkansas, USA

U.S. Food and Drug Administration, National Center for Toxicological Research, Jefferson, Arkansas, USA.

出版信息

Genome Announc. 2017 Nov 9;5(45):e01222-17. doi: 10.1128/genomeA.01222-17.

DOI:10.1128/genomeA.01222-17
PMID:29122873
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5679806/
Abstract

We report here the draft genome sequences of 15 ciprofloxacin-resistant strains with resistance to multiple other antibiotics, including aminoglycosides, β-lactams, sulfonamides, tetracycline, and trimethoprim, isolated from different imported foods. Three strains (NCTR75, NCTR281, and NCTR350) showed a high level of ciprofloxacin resistance compared to that of the other isolates. The whole-genome sequencing data provide a better understanding of the antibiotic resistance mechanisms and virulence properties of these isolates.

摘要

我们在此报告从不同进口食品中分离出的15株对环丙沙星耐药且对多种其他抗生素(包括氨基糖苷类、β-内酰胺类、磺胺类、四环素和甲氧苄啶)耐药的菌株的基因组序列草图。与其他分离株相比,三株菌株(NCTR75、NCTR281和NCTR350)显示出高水平的环丙沙星耐药性。全基因组测序数据有助于更好地了解这些分离株的抗生素耐药机制和毒力特性。

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