Edelmann Cathrin, Ghiassi Ramesh, Vogt Deborah R, Partridge Martyn R, Khatami Ramin, Leuppi Jörg D, Miedinger David
Medical Faculty, University of Basel, Basel, Switzerland.
National Heart and Lung Institute, Imperial College London, London, UK.
Nat Sci Sleep. 2017 Oct 25;9:253-265. doi: 10.2147/NSS.S139936. eCollection 2017.
The aim of this study was to evaluate the validity of a new pictorial form of a screening test for obstructive sleep apnea syndrome (OSAS) - the pictorial Sleepiness and Sleep Apnoea Scale (pSSAS). Validation was performed in a sample of patients admitted to sleep clinics in the UK and Switzerland.
All study participants were investigated with objective sleep tests such as full-night-attended polysomnography or polygraphy. The pSSAS was validated by taking into account the individual result of the sleep study, sleep-related questionnaires and objective parameters such as body mass index (BMI) or neck circumference. Different scoring schemes of the pSSAS were evaluated, and an internal validation was undertaken.
The full data set consisted of 431 individuals (234 patients from the UK, 197 patients from Switzerland). The pSSAS showed good predictive performance for OSAS with an area under the curve between 0.77 and 0.81 depending on which scoring scheme was used. The subscores of the pSSAS had a moderate-to-strong correlation with widely used screening questionnaires for OSAS or excessive daytime sleepiness as well as with BMI and neck circumference.
The pSSAS can be used to select patients with a high probability of having OSAS. Due to its simple pictorial design with short questions, it might be suitable for screening in populations with low health literacy and in non-native English or German speakers.
本研究旨在评估一种用于阻塞性睡眠呼吸暂停综合征（OSAS）筛查测试的新图形形式——图形嗜睡与睡眠呼吸暂停量表（pSSAS）的有效性。在英国和瑞士睡眠诊所收治的患者样本中进行了验证。
所有研究参与者均接受了客观睡眠测试，如整夜多导睡眠监测或睡眠监测仪检查。通过考虑睡眠研究的个体结果、与睡眠相关的问卷以及诸如体重指数（BMI）或颈围等客观参数来验证pSSAS。评估了pSSAS的不同评分方案，并进行了内部验证。
完整数据集包括431名个体（234名来自英国的患者，197名来自瑞士的患者）。根据所使用的评分方案，pSSAS对OSAS显示出良好的预测性能，曲线下面积在0.77至0.81之间。pSSAS的子评分与广泛使用的OSAS或日间过度嗜睡筛查问卷以及BMI和颈围具有中度至强相关性。
pSSAS可用于筛选患有OSAS可能性较高的患者。由于其简单的图形设计和简短的问题，它可能适用于健康素养较低的人群以及非英语或德语母语者的筛查。
