Li Qingrui, Zhao Xiuli, Li Yabo, Huang Mengmeng, Kim Jung Keun, Wu Yangjie
College of Chemistry and Molecular Engineering, Henan Key Laboratory of Chemical Biology and Organic Chemistry, Key Laboratory of Applied Chemistry of Henan Universities, Zhengzhou University, Zhengzhou, 450052, P.R. China.
Org Biomol Chem. 2017 Nov 29;15(46):9775-9778. doi: 10.1039/c7ob02478a.
The regioselective synthesis of 3-phosphinylated coumarins in moderate to excellent yields was developed via an EY/BPO-mediated cross-dehydrogenative coupling (CDC) reaction under green LED irradiation. The results of control experiments showed that the active intermediate, a P-centered radical, might be obtained through energy transfer and electron transfer processes.
通过EY/BPO介导的交叉脱氢偶联（CDC）反应，在绿色LED光照下，以中等至优异的产率实现了3-膦酰基香豆素的区域选择性合成。对照实验结果表明，活性中间体，即一个以磷为中心的自由基，可能是通过能量转移和电子转移过程得到的。
