Drevets W C, Rubin E H
Department of Psychiatry, Washington University School of Medicine, St. Louis, MO 63110.
Biol Psychiatry. 1989 Jan;25(1):39-48. doi: 10.1016/0006-3223(89)90145-5.
Delusions, misidentifications and hallucinations occur frequently throughout the course of senile dementia of the Alzheimer type (SDAT). Rates of psychosis among subjects with moderate to severe SDAT range from 42% to 84% in our study group; at least half of persons with SDAT with no prior psychiatric history will display psychosis at some point during the course of dementia. Furthermore, psychotic symptoms are associated with accelerated cognitive deterioration, but not with increased mortality.
在阿尔茨海默病型老年痴呆症（SDAT）病程中，妄想、错认和幻觉频繁出现。在我们的研究组中，中重度SDAT患者的精神病发生率在42%至84%之间；至少一半无精神病史的SDAT患者在痴呆病程的某个阶段会出现精神病症状。此外，精神病症状与认知功能加速衰退相关，但与死亡率增加无关。
