Baldwin Katherine R, Kaplan Jess L
Pediatric Gastroenterology and Nutrition, MassGeneral Hospital for Children, Harvard Medical School, Boston, MA.
Pediatric Gastroenterology and Nutrition, MassGeneral Hospital for Children, Harvard Medical School, Boston, MA.
Semin Pediatr Surg. 2017 Dec;26(6):360-366. doi: 10.1053/j.sempedsurg.2017.10.005. Epub 2017 Oct 5.
Inflammatory bowel diseases (IBD) are chronic autoimmune conditions of the gut affecting both pediatric and adult patients. Medical therapy is often successful at inducing and maintaining remission and preventing disease complications. The mainstays of treatment are medications and other therapies that reduce inflammation and suppress the overactive immune system. Here we review current medical therapies for pediatric IBD, discuss future therapeutics, and present current treatment goals and approaches.
炎症性肠病(IBD)是一种影响儿童和成人患者的肠道慢性自身免疫性疾病。药物治疗通常能成功诱导和维持缓解,并预防疾病并发症。治疗的主要手段是使用药物和其他疗法来减轻炎症并抑制过度活跃的免疫系统。在此,我们综述了目前用于儿童IBD的药物治疗方法,讨论了未来的治疗手段,并介绍了当前的治疗目标和方法。