Siow Vei Shaun, Bhatt Riha, Mollen Kevin P
Department of Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
Division of Gastroenterology, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, Pennsylvania.
Semin Pediatr Surg. 2017 Dec;26(6):367-372. doi: 10.1053/j.sempedsurg.2017.10.006. Epub 2017 Oct 5.
The incidence of pediatric-onset ulcerative colitis (UC) is rising. Children often present with a more severe disease phenotype as compared to adults with over a third requiring hospitalization for the management of acute severe ulcerative colitis (ASUC). Further, in pediatric patients presenting with inflammatory bowel disease (IBD) limited to the colon, a definitive diagnosis of UC vs. Crohn's disease is often unclear. Here, we review the unique aspects of pediatric ASUC including the epidemiology, diagnosis, medical, and surgical management of this disease.
儿童期溃疡性结肠炎（UC）的发病率正在上升。与成人相比，儿童常表现出更严重的疾病表型，超过三分之一的儿童因急性重症溃疡性结肠炎（ASUC）的治疗需要住院。此外，在仅表现为结肠炎症性肠病（IBD）的儿科患者中，UC与克罗恩病的明确诊断往往不明确。在此，我们综述了儿童ASUC的独特方面，包括该疾病的流行病学、诊断、内科和外科治疗。
