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一名儿童出现无色素性肉阜样病变的恶性黑色素瘤。

Malignant melanoma presenting as amelanotic caruncular lesion in a child.

作者信息

Walters Alexander R, Keck Katie M, Simmons Oliver, Williams Sarah G, Cross Stephen, Patel Rakesh M

机构信息

Department of Ophthalmology, Palmetto Health/University of South Carolina, Richland.

Department of Ophthalmology, Palmetto Health/University of South Carolina, Richland.

出版信息

J AAPOS. 2017 Dec;21(6):501-503. doi: 10.1016/j.jaapos.2017.06.025. Epub 2017 Nov 7.

Abstract

Conjunctival melanoma is a rare malignant neoplasm that can present in childhood in any part of the conjunctiva. The infrequency with which conjunctival melanoma is encountered in childhood caruncular lesions makes it a formidable but important aspect of the differential diagnosis. We report the case of a 10-year-old boy who presented with a left caruncular lesion. On histopathologic analysis, the lesion was determined to be BRAF-negative invasive melanoma arising in association with melanocytic nevus. The melanoma was excised using no-touch technique and double freeze thaw cryotherapy. A full systemic work-up revealed no metastasis or abnormality.

摘要

结膜黑色素瘤是一种罕见的恶性肿瘤,可在儿童期出现在结膜的任何部位。儿童泪阜病变中结膜黑色素瘤的罕见性使其成为鉴别诊断中一个棘手但重要的方面。我们报告一例10岁男孩,其出现左侧泪阜病变。经组织病理学分析,该病变被确定为与黑素细胞痣相关的BRAF阴性浸润性黑色素瘤。采用非接触技术和双重冻融冷冻疗法切除黑色素瘤。全面的全身检查未发现转移或异常。

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