Department of Urology, Christian Medical College, Vellore, India.
Department of Pathology, Christian Medical College, Vellore, India.
J Stomatol Oral Maxillofac Surg. 2018 Apr;119(2):145-147. doi: 10.1016/j.jormas.2017.11.002. Epub 2017 Nov 8.
Renal cell carcinoma (RCC) is the third most common genitourinary malignancy with an estimated one third of cases with metastatic disease at the time of diagnosis. Though rare, cutaneous metastasis from RCC is more frequent than any other genitourinary malignancy. Metastasis of RCC to skin carries poor prognosis as coexistent visceral spread is the norm. A 38-year-old man presented one year after radical nephrectomy for clear cell carcinoma of the left kidney with a submental lesion that proved to be metastatic. Clinical appearance of cutaneous RCC metastasis is varied and can closely mimic other skin lesions. It is incumbent on general practitioners, dermatologists and urologists to exercise diligence in clinical diagnosis of skin lesions in the background of previous oncological diagnosis.
肾细胞癌（RCC）是第三大常见的泌尿生殖系统恶性肿瘤，约有三分之一的病例在诊断时已发生转移。虽然罕见，但 RCC 的皮肤转移比任何其他泌尿生殖系统恶性肿瘤都更常见。RCC 皮肤转移预后不良，因为通常同时存在内脏转移。一名 38 岁男性在因左肾透明细胞癌行根治性肾切除术一年后出现颏下病变，证实为转移性病变。RCC 皮肤转移的临床外观多种多样，可与其他皮肤病变非常相似。在既往肿瘤学诊断的背景下，普通科医生、皮肤科医生和泌尿科医生有责任在皮肤病变的临床诊断中保持警惕。
