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皮肤转移作为肾细胞癌的首发症状——文献分析与自身观察的交叉点

Cutaneous metastasis as the first sign of renal cell carcinoma - crossroad between literature analysis and own observations.

作者信息

Balawender Krzysztof, Przybyła Rafał, Orkisz Stanisław, Wawrzyniak Agata, Boroñ Dariusz, Grabarek Beniamin O

机构信息

Clinical Department of Urology and Urological Oncology, Municipal Hospital, Rzeszow, Poland.

Morphological Sciences Department of Human Anatomy Institute of Medical Sciences, Medical College of Rzeszow University, Rzeszow, Poland.

出版信息

Postepy Dermatol Alergol. 2022 Jun;39(3):553-558. doi: 10.5114/ada.2021.108275. Epub 2021 Aug 2.

Abstract

INTRODUCTION

Metastatic disease can be observed in nearly 25% of all renal cell carcinoma cases (RCC). This can present in the skin as a late symptom of the disease or as a manifestation of an undetected, asymptomatic RCC.

AIM

To review the literature and present a case study of cutaneous metastasis in primary genitourinary malignancy, especially RCC in order to broaden the related knowledge.

MATERIAL AND METHODS

The first stage of our work was focused on presenting the results of the literature review about cutaneous metastasis in the patients with renal cell carcinoma. Next, taking into account that this type of metastasis associated with RCC is relatively rare, we have decided to present a patient aged 68 with incidentally detected skin metastases of RCC located on the scalp.

RESULTS

It was diagnosed as a primary manifestation of advanced disease. Computed tomography scans showed a solid mass in the left kidney. Following surgical excision of the skin lesion, a left-side nephrectomy was performed.

CONCLUSIONS

Cutaneous metastases of RCC present an unfavourable prognosis, however, remission is possible subsequent to early diagnosis and appropriate surgical excision.

摘要

引言

在所有肾细胞癌(RCC)病例中,近25%会出现转移疾病。这可能表现为疾病的晚期症状出现在皮肤,或作为未被发现的无症状肾细胞癌的一种表现。

目的

回顾文献并呈现原发性泌尿生殖系统恶性肿瘤,尤其是肾细胞癌皮肤转移的病例研究,以拓宽相关知识。

材料与方法

我们工作的第一阶段专注于呈现肾细胞癌患者皮肤转移的文献综述结果。接下来,考虑到这种与肾细胞癌相关的转移类型相对罕见,我们决定呈现一名68岁患者,其头皮上偶然发现肾细胞癌的皮肤转移。

结果

它被诊断为晚期疾病的主要表现。计算机断层扫描显示左肾有一个实性肿块。在手术切除皮肤病变后,进行了左侧肾切除术。

结论

肾细胞癌的皮肤转移预后不佳,然而,早期诊断并进行适当的手术切除后有可能缓解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/752a/9326906/2af90925eeb4/PDIA-39-44889-g001.jpg

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