Lorenzo-Rios Deyson, Cruzval-O'Reilly Estefania, Rabelo-Cartagena Jose
Dermatology, University of Puerto Rico, San Juan, PRI.
Dermatology, Universidad Central del Caribe School of Medicine, Bayamón, PRI.
Cureus. 2020 Dec 15;12(12):e12093. doi: 10.7759/cureus.12093.
Renal cell carcinoma (RCC) is a common genitourinary malignancy of increasing incidence and significant mortality rate. Skin metastases of RCC are considered a rare phenomenon of unfavorable outcomes. We present a 75-year-old male patient who developed a rapidly evolving lesion on his left cheek four years after undergoing a right radical nephrectomy for non-metastatic RCC. Immunohistochemistry of the skin lesion was diagnostic for cutaneous metastasis of renal clear cell carcinoma, which eventually led to the detection of internal malignancy recurrence by positron emission tomography. A new facial skin lesion may unmask the underlying recurrence of RCC.
肾细胞癌（RCC）是一种常见的泌尿生殖系统恶性肿瘤，其发病率不断上升，死亡率颇高。RCC的皮肤转移被认为是一种罕见现象，预后不佳。我们报告一例75岁男性患者，他在因非转移性RCC接受右肾根治性切除术后四年，左侧脸颊出现一个迅速发展的病变。皮肤病变的免疫组织化学检查诊断为肾透明细胞癌皮肤转移，最终通过正电子发射断层扫描检测到体内恶性肿瘤复发。新出现的面部皮肤病变可能会揭示RCC潜在的复发情况。
