铜蓝蛋白在刺激齿垢密螺旋体生长方面可替代兔血清。
Ceruloplasmin can substitute for rabbit serum in stimulating the growth of Treponema denticola.
作者信息
Suzuki M, Loesche W J
机构信息
Department of Biologic and Materials Sciences, School of Dentistry, University of Michigan, Ann Arbor 48109-1078.
出版信息
Infect Immun. 1989 Feb;57(2):643-4. doi: 10.1128/iai.57.2.643-644.1989.
The growth of Treponema denticola in a complex medium was stimulated by human ceruloplasmin and, to a lesser extent, albumin, alpha-1-antitrypsin, alpha-1-acid glycoprotein, and alpha-2-macroglobulin. Human ceruloplasmin could stimulate growth of T. denticola as well as or better than 5% rabbit serum, with a dose-response relationship of between 1 and 5 mg of ceruloplasmin per ml of culture medium. These results suggest that ceruloplasmin could substitute for rabbit serum in stimulating the growth of T. denticola.
人类铜蓝蛋白可刺激齿垢密螺旋体在复合培养基中的生长，白蛋白、α-1抗胰蛋白酶、α-1酸性糖蛋白和α-2巨球蛋白在较小程度上也有此作用。人类铜蓝蛋白刺激齿垢密螺旋体生长的效果与5%兔血清相当或更佳，每毫升培养基中铜蓝蛋白剂量在1至5毫克时存在剂量反应关系。这些结果表明，铜蓝蛋白在刺激齿垢密螺旋体生长方面可替代兔血清。
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