癫痫中的注意力缺陷多动障碍（ADHD）与原发性ADHD：症状维度及生活质量的差异
Attention-Deficit Hyperactivity Disorder (ADHD) in Epilepsy and Primary ADHD: Differences in Symptom Dimensions and Quality of Life.
作者信息
Ekinci Ozalp, Okuyaz Çetin, Erdoğan Semra, Gunes Serkan, Ekinci Nuran, Kalınlı Merve, Teke Halenur, Direk Meltem Çobanoğulları
机构信息
1 Department of Child and Adolescent Psychiatry, University of Health Sciences Medical Faculty, Istanbul, Turkey.
2 Department of Pediatric Neurology, Mersin University Medical Faculty, Mersin, Turkey.
出版信息
J Child Neurol. 2017 Dec;32(14):1083-1091. doi: 10.1177/0883073817737445.
PURPOSE
We aimed to (1) compare quality of life (QOL) among children with epilepsy, epilepsy and attention-deficit hyperactivity disorder (ADHD), and primary ADHD and (2) compare ADHD symptom dimensions and subtypes between children with epilepsy-ADHD and primary ADHD.
METHODS
A total of 140 children; 53 with epilepsy, 35 with epilepsy-ADHD, and 52 with primary ADHD were included. KINDL-R (quality of life measure), Turgay DSM-IV Disruptive Behavior Disorders Rating Scale (T-DSM-IV-S), and Conners' Parent Rating Scale (CPRS) were completed. Neurology clinic charts were reviewed for epilepsy-related variables.
RESULTS
Children with epilepsy-ADHD had the lowest (poorest) KINDL-R total scores. Epilepsy-ADHD group had more inattentiveness symptoms, whereas primary ADHD group had more hyperactivity/impulsivity symptoms. The frequencies of ADHD combined and inattentiveness subtypes were 60% and 40% in children with epilepsy-ADHD and 80.7% and 19.3% in children with primary ADHD, respectively ( P = .034).
CONCLUSION
ADHD in epilepsy is associated with a significantly poor quality of life and predominantly inattentiveness symptoms.
目的
我们旨在（1）比较癫痫患儿、癫痫合并注意力缺陷多动障碍（ADHD）患儿以及原发性ADHD患儿的生活质量（QOL），（2）比较癫痫合并ADHD患儿与原发性ADHD患儿的ADHD症状维度及亚型。
方法
共纳入140名儿童，其中53名癫痫患儿、35名癫痫合并ADHD患儿以及52名原发性ADHD患儿。完成了儿童生活质量量表（KINDL-R）、图尔盖DSM-IV破坏性行为障碍评定量表（T-DSM-IV-S）以及康纳斯父母评定量表（CPRS）。查阅神经科门诊病历以获取癫痫相关变量。
结果
癫痫合并ADHD患儿的KINDL-R总分最低（最差）。癫痫合并ADHD组注意力不集中症状更多，而原发性ADHD组多动/冲动症状更多。癫痫合并ADHD患儿中ADHD混合型和注意力不集中型的频率分别为60%和40%，原发性ADHD患儿中分别为80.7%和19.3%（P = .034）。
结论
癫痫中的ADHD与显著较差的生活质量以及主要的注意力不集中症状相关。
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