Suppr超能文献

睾丸生殖细胞肿瘤的胃肠道受累:一例报告及文献综述

Gastrointestinal Involvement of Testicular Germ Cell Tumor: A Case Report and Literature Review.

作者信息

Shogbesan Oluwaseun, Abdulkareem Abdullateef, Jehangir Asad, Byreddy Sunila, Swierczynski Sharon, Donato Anthony

机构信息

Department of Internal Medicine, Reading Health System, Sixth Avenue and Spruce Street, West Reading, PA 19611, USA.

Hospitalist Services, Reading Health System, Sixth Avenue and Spruce Street, West Reading, PA 19611, USA.

出版信息

Case Rep Gastrointest Med. 2017;2017:4789259. doi: 10.1155/2017/4789259. Epub 2017 Oct 10.

Abstract

Testicular germ cell tumors (GCT) are the commonest solid tumors in young men. Typical presentation is with painless scrotal swelling; however, symptoms related to complications or metastasis may be the initial presentation. Gastrointestinal (GI) metastasis is seen in about 5% of patients with germ cell tumors and presentation is commonly with GI bleed. It is important to have GCT as a differential diagnosis of GI bleed in young men presenting with unexplained anemia as direct questioning about scrotal swelling and genital examination when appropriate will guide further investigation and facilitate prompt diagnosis. We present a case of a 26-year-old man with testicular germ cell tumor and severe anemia secondary to extension and perforation of duodenum by retroperitoneal metastasis and a review of the literature on the gastrointestinal manifestations of testicular germ cell tumors.

摘要

睾丸生殖细胞肿瘤(GCT)是年轻男性中最常见的实体瘤。典型表现为无痛性阴囊肿大;然而,与并发症或转移相关的症状可能是首发表现。约5%的生殖细胞肿瘤患者会出现胃肠道(GI)转移,通常表现为GI出血。对于出现不明原因贫血的年轻男性,将GCT作为GI出血的鉴别诊断很重要,因为直接询问阴囊肿大情况并在适当时候进行生殖器检查将有助于进一步检查并促进及时诊断。我们报告一例26岁男性睾丸生殖细胞肿瘤患者,因腹膜后转移导致十二指肠延伸和穿孔继发严重贫血,并对睾丸生殖细胞肿瘤的胃肠道表现相关文献进行综述。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0285/5654329/b75beee7a8a9/CRIGM2017-4789259.001.jpg

相似文献

1
Gastrointestinal Involvement of Testicular Germ Cell Tumor: A Case Report and Literature Review.
Case Rep Gastrointest Med. 2017;2017:4789259. doi: 10.1155/2017/4789259. Epub 2017 Oct 10.
2
Testicular tumors in children.
J Pediatr Surg. 2001 Dec;36(12):1796-801. doi: 10.1053/jpsu.2001.28841.
3
Small Bowel Metastasis as a Presentation of Testicular Seminoma.
Cureus. 2021 Sep 14;13(9):e17962. doi: 10.7759/cureus.17962. eCollection 2021 Sep.
4
Isolated bone metastasis in testicular germ cell tumors: a case report and review of the literature.
Onkologie. 2006 Mar;29(3):93-5. doi: 10.1159/000091149. Epub 2006 Mar 3.
6
Testicular choriocarcinoma with small bowel metastasis and active gastrointestinal bleeding.
Radiol Case Rep. 2023 Jan 6;18(3):1117-1120. doi: 10.1016/j.radcr.2022.12.019. eCollection 2023 Mar.
7
Vision Loss as Presenting Symptom in Testicular Cancer: A Morbid Case Report.
Case Rep Ophthalmol. 2022 Sep 30;13(3):756-762. doi: 10.1159/000526748. eCollection 2022 Sep-Dec.
8
Gastrointestinal presentation of germ cell malignancy.
Eur Urol. 2000 Dec;38(6):721-4. doi: 10.1159/000020368.
9
10
A Case of Testicular Tumor Presenting as Acute Scrotum.
Cureus. 2023 Aug 27;15(8):e44185. doi: 10.7759/cureus.44185. eCollection 2023 Aug.

引用本文的文献

2
Small bowel metastases from a testicular choriocarcinoma revealed by gastrointestinal bleeding: a case report.
Pan Afr Med J. 2021 Aug 20;39:259. doi: 10.11604/pamj.2021.39.259.30325. eCollection 2021.
3
Duodenal ulcer bleeding led to the first diagnosis of testicular cancer.
BMJ Case Rep. 2021 Oct 19;14(10):e246270. doi: 10.1136/bcr-2021-246270.
4
Metastatic Testicular Embryonal Carcinoma Presenting as Gastrointestinal Hemorrhage.
ACG Case Rep J. 2021 Sep 14;8(9):e00654. doi: 10.14309/crj.0000000000000654. eCollection 2021 Sep.

本文引用的文献

1
Recovery from Choriocarcinoma Syndrome Associated with a Metastatic Extragonadal Germ Cell Tumor Hemorrhage.
Case Rep Gastroenterol. 2016 May 19;10(1):193-8. doi: 10.1159/000446017. eCollection 2016 Jan-Apr.
2
Cancer statistics, 2016.
CA Cancer J Clin. 2016 Jan-Feb;66(1):7-30. doi: 10.3322/caac.21332. Epub 2016 Jan 7.
3
Testicular choriocarcinoma: a rare variant that requires a unique treatment approach.
Curr Oncol Rep. 2015 Feb;17(2):2. doi: 10.1007/s11912-014-0430-0.
4
Increased stomach cancer risk following radiotherapy for testicular cancer.
Br J Cancer. 2015 Jan 6;112(1):44-51. doi: 10.1038/bjc.2014.552. Epub 2014 Nov 4.
5
Second cancer risk and mortality in men treated with radiotherapy for stage I seminoma.
Br J Cancer. 2014 Jan 7;110(1):256-63. doi: 10.1038/bjc.2013.551. Epub 2013 Nov 21.
6
Innovations in health care and mortality trends from five cancers in seven European countries between 1970 and 2005.
Int J Public Health. 2014 Apr;59(2):341-50. doi: 10.1007/s00038-013-0507-9. Epub 2013 Aug 29.
8
A rare case of primary seminoma of the small bowel with lymph node involvement.
J Gastrointest Cancer. 2011 Sep;42(3):183-5. doi: 10.1007/s12029-010-9177-5.
9
Second cancers after testicular cancer diagnosed after 1980 in Sweden.
Ann Oncol. 2010 Jul;21(7):1546-1551. doi: 10.1093/annonc/mdp562. Epub 2009 Dec 17.
10
Upper gastrointestinal bleeding from metastatic testicular cancer.
J Natl Med Assoc. 2009 Aug;101(8):808-9. doi: 10.1016/s0027-9684(15)31011-7.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验