Department of Persian Medicine, School of Persian and Complementary Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Department of Ear, Nose and Throat, Mashhad university of medical sciences, Mashhad, Iran.
Phytother Res. 2018 Mar;32(3):395-401. doi: 10.1002/ptr.5968. Epub 2017 Nov 12.
Chronic rhinosinusitis (CRS) is a common disease with evidence to show that its incidence and prevalence are increasing. Medicinal plants are commonly used to treat CRS. This systematic review aimed to assess the effectiveness and safety of herbal preparations for treatment of the patients with CRS. Cochran, Embase, ISI, PubMed, and Scopus databases were searched until August 1, 2016. Only randomized controlled trials were included. Four randomized controlled trials were included in this systematic review. Various medicinal plants were studied in each article. Inclusion and exclusion criteria, and outcome measures varied among different articles. The results of this trials showed that this special medicinal plants may be effective in the treatment of CRS. No serious reactions were reported during the administration of herbal remedies in the 4 studies. However, trials with a well-designed approach are needed to study the actual safety and efficacy of herbs in the treatment of CRS.
慢性鼻-鼻窦炎（CRS）是一种常见疾病，有证据表明其发病率和患病率正在增加。草药通常被用于治疗 CRS。本系统评价旨在评估草药制剂治疗 CRS 患者的有效性和安全性。我们检索了 Cochran、Embase、ISI、PubMed 和 Scopus 数据库，检索时间截至 2016 年 8 月 1 日。仅纳入随机对照试验。本系统评价纳入了 4 项随机对照试验。在每篇文章中都研究了各种药用植物。不同文章的纳入和排除标准以及结局指标各不相同。这些试验结果表明，这些特殊的药用植物可能对 CRS 的治疗有效。在 4 项研究中，在给予草药治疗期间未报告严重反应。然而，需要采用精心设计的方法来研究草药在治疗 CRS 中的实际安全性和疗效。
