2017 年加拿大耐头孢曲松淋病奈瑟菌。
Ceftriaxone-Resistant Neisseria gonorrhoeae, Canada, 2017.
出版信息
Emerg Infect Dis. 2018 Feb;24(2):381-3. doi: 10.3201/eid2402.171756. Epub 2018 Feb 17.
Abstract
We identified a ceftriaxone-resistant Neisseria gonorrhoeae isolate in a patient in Canada. This isolate carried the penA-60 allele, which differs substantially from its closest relative, mosaic penA XXVII (80% nucleotide identity). Epidemiologic and genomic data suggest spread from Asia. Antimicrobial susceptibility surveillance helps prevent spread of highly resistant N. gonorrhoeae strains.
摘要
我们在加拿大的一位患者身上发现了一株对头孢曲松耐药的淋病奈瑟菌分离株。该分离株携带 penA-60 等位基因，与最接近的亲缘关系——马赛克 penA XXVII（80%核苷酸同一性）有很大的不同。流行病学和基因组数据表明该分离株源自亚洲。抗菌药物敏感性监测有助于防止高度耐药淋病奈瑟菌株的传播。
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