加拿大广泛耐药淋病奈瑟菌菌株

Extensively Drug-Resistant Neisseria gonorrhoeae Strain, Canada.

作者信息

Lefebvre Brigitte, Martin Irene, Thorington Robyn, Gitelman Julian, Bui-Nguyen Andrew, Fortin Claude, Fafard Judith

出版信息

Emerg Infect Dis. 2025 Jul;31(7):1446-1449. doi: 10.3201/eid3107.250023.

DOI:10.3201/eid3107.250023

PMID:40563105

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12205461/

Abstract

We identified a case of extensively drug-resistant (ceftriaxone- and cefixime-resistant and high-level azithromycin-resistant) Neisseria gonorrhoeae in Canada. The strain harbors the penA 60.001 allele, which includes the A311V and 23S rRNA A2059G single-nucleotide polymorphisms associated with high-level azithromycin resistance. The infection was likely acquired during travel in Cambodia.

摘要

我们在加拿大发现了一例广泛耐药（对头孢曲松和头孢克肟耐药且对阿奇霉素高度耐药）的淋病奈瑟菌病例。该菌株携带penA 60.001等位基因，其中包括与阿奇霉素高度耐药相关的A311V和23S rRNA A2059G单核苷酸多态性。该感染可能是在柬埔寨旅行期间获得的。