Khokhar Sudarshan, Jose Cijin P, Sihota Ramanjit, Midha Neha
J Pediatr Ophthalmol Strabismus. 2018 Mar 1;55(2):107-112. doi: 10.3928/01913913-20170703-11. Epub 2017 Nov 14.
To study the clinical profile and presentation of children with unilateral cataract.
In this hospital-based, observational, cross-sectional study, patients 15 years of age or younger who presented with unilateral cataract were recruited. Cases of cataract secondary to causes such as trauma or uveitis were excluded. Age at detection and presentation, distance from the treatment center, presenting complaints, cataract morphology, and biometry were noted for each case.
A total of 76 patients were recruited. Most patients presented with complaints of leukocoria. Persistent fetal vasculature accounted for 27.6% of cases and was the most common identifiable cause of cataract in this study. Subsequently, patients were divided into two groups: no persistent fetal vasculature (control) and persistent fetal vasculature. A male predominance was noted in both groups. The mean age at detection was 27.58 ± 37.02 and 6.17 ± 8.42 months and the mean age at presentation was 55.613 ± 45.21 and 14.83 ± 17.75 months in the control and persistent fetal vasculature groups, respectively. In the persistent fetal vasculature group, a significant difference was noted in the axial length, keratometry, and corneal diameter between the affected and normal eyes (P = .027, .00176, and .0114, respectively). In the control group, this difference was observed only in keratometry readings (P = .0464). The mean distance traveled by patients to reach the treatment center was 211 km.
Persistent fetal vasculature is an important and less identified cause of unilateral cataract. A significant delay is noted in the detection and presentation of unilateral cataract. [J Pediatr Ophthalmol Strabismus. 2018;55(2):107-112.].
研究单侧白内障患儿的临床特征及表现。
在这项基于医院的观察性横断面研究中，招募了15岁及以下患有单侧白内障的患者。排除因外伤或葡萄膜炎等原因导致的继发性白内障病例。记录每个病例的发现年龄和就诊年龄、距治疗中心的距离、就诊主诉、白内障形态及生物测量数据。
共招募了76例患者。大多数患者的主诉为白瞳症。永存原始玻璃体增生症占病例的27.6%，是本研究中最常见的可识别白内障病因。随后，患者被分为两组：无永存原始玻璃体增生症（对照组）和永存原始玻璃体增生症组。两组均以男性为主。对照组和永存原始玻璃体增生症组的平均发现年龄分别为27.58±37.02个月和6.17±8.42个月，平均就诊年龄分别为55.613±45.21个月和14.83±17.75个月。在永存原始玻璃体增生症组中，患眼与正常眼之间的眼轴长度、角膜曲率和角膜直径存在显著差异（分别为P = 0.027、0.00176和0.0114）。在对照组中，仅在角膜曲率读数中观察到这种差异（P = 0.0464）。患者到达治疗中心的平均路程为211公里。
永存原始玻璃体增生症是单侧白内障的一个重要且较少被认识到的病因。单侧白内障的发现和就诊存在显著延迟。[《小儿眼科与斜视杂志》。2018；55(2)：107 - 112。]
