Xue Chao-Chao, Liang Ya-Feng, Pan Guo-Quan, Li Chang-Chong
Department of Pediatrics, Second Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325000, China.
Zhongguo Dang Dai Er Ke Za Zhi. 2017 Nov;19(11):1191-1195. doi: 10.7499/j.issn.1008-8830.2017.11.013.
To study the clinical features and prognosis of benign infantile convulsions associated with mild gastroenteritis (BICE).
A retrospective analysis was performed for the clinical data of 436 children with BICE, and among these children, 206 were followed up for 1.5 to 7 years. Some parents were invited to complete the Weiss Functional Defect Scale to evaluate the long-term social function.
The peak age of onset of BICE was 13-24 months, and BICE had a higher prevalence rate in September to February of the following year. Convulsions mainly manifested as generalized tonic-clonic seizures, which often occurred within 24 hours after disease onset and lasted for less than 5 minutes each time. Sometimes they occurred in clusters. During the follow-up of 206 children, only one had epileptiform discharge, and the other children had normal electroencephalographic results. The parents of all the 206 children thought their children had normal intelligence and had no marked changes in character. Based on the Weiss Functional Defect Scale completed by the parents of some BICE children, there was no significant difference in the long-term social function between BICE children and healthy children matched by age and sex.
BICE mainly occurs in children aged 1-2 years, with the manifestation of transient generalized seizures in most children and cluster seizures in some children. BICE seldom progresses to epilepsy and has good prognosis.
研究轻度胃肠炎伴良性婴儿惊厥（BICE）的临床特征及预后。
对436例BICE患儿的临床资料进行回顾性分析，其中206例患儿进行了1.5至7年的随访。邀请部分家长完成维斯功能缺陷量表以评估长期社会功能。
BICE的发病高峰年龄为13 - 24个月，在9月至次年2月患病率较高。惊厥主要表现为全身性强直阵挛发作，常在发病后24小时内出现，每次持续时间少于5分钟，有时呈簇状发作。在对206例患儿的随访中，仅1例有癫痫样放电，其余患儿脑电图结果正常。206例患儿的家长均认为其孩子智力正常，性格无明显改变。根据部分BICE患儿家长完成的维斯功能缺陷量表，BICE患儿与年龄、性别匹配的健康儿童在长期社会功能方面无显著差异。
BICE主要发生于1 - 2岁儿童，多数患儿表现为短暂性全身性发作，部分患儿呈簇状发作。BICE很少进展为癫痫，预后良好。
