Parrish Christopher P, Kim Edwin H, Bird J Andrew
Food Allergy Center at Children's Medical Center, 1935 Medical District Drive, Dallas, TX 75235, USA.
Division of Rheumatology, Allergy and Immunology, University of North Carolina-Chapel Hill, 3300 Thurston Building, Campus Box 7280, Chapel Hill, NC 27599-7280, USA.
Immunol Allergy Clin North Am. 2018 Feb;38(1):77-88. doi: 10.1016/j.iac.2017.09.006. Epub 2017 Oct 23.
Treatment of IgE-mediated food allergies is limited to allergen avoidance and emergency treatment on accidental ingestion, which is not uncommon. In recent years, interest in interventional therapies to treat food allergy has increased significantly. Although oral, sublingual, and epicutaneous immunotherapy have shown promise in studies, none is approved as therapy for food allergy to date and questions remain regarding efficacy, safety, dosing, and duration of therapy.
IgE介导的食物过敏的治疗仅限于避免接触过敏原以及在意外摄入时进行紧急治疗,这种情况并不罕见。近年来,对治疗食物过敏的介入疗法的兴趣显著增加。尽管口服、舌下和经皮免疫疗法在研究中显示出前景,但迄今为止尚无一种被批准用于食物过敏的治疗,关于疗效、安全性、剂量和治疗持续时间仍存在疑问。