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重症监护病房患者在接受益生菌治疗后发生酵母菌血症。

Saccharomyces cerevisiae fungemia after probiotic treatment in an intensive care unit patient.

机构信息

Gazi University Faculty of Medicine, Anaesthesia and Reanimation Division, Ankara, Turkey.

Department of Infectious Disease and Clinical Microbiology, Ankara, Turkey.

出版信息

J Mycol Med. 2018 Mar;28(1):218-221. doi: 10.1016/j.mycmed.2017.09.003. Epub 2017 Nov 11.

DOI:10.1016/j.mycmed.2017.09.003
PMID:29132794
Abstract

Saccharomyces cerevisiae is a common colonizer of the human gastrointestinal system as a benign organism. Enteral supplementation of this yeast as a probiotic product is effective in the treatment of antibiotic associated diarrhae. In rare occasions it can cause invasive infections. We present two fungemia cases in an intensive care unit following probiotic treatment containing S. boulardii. We are warning the safety of probiotic treatment in critically ill patients.

摘要

酿酒酵母是一种常见的人类胃肠道良性定植菌。作为益生菌产品，经肠道补充这种酵母对治疗抗生素相关性腹泻是有效的。但在极少数情况下，它可能会引起侵袭性感染。我们报告了两例重症监护病房患者在使用含有布拉氏酵母菌的益生菌治疗后发生真菌血症的病例。我们对重症患者应用益生菌治疗的安全性提出警告。

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