Klügel Stephanie, Lücke Caroline, Meta Aurora, Schild-Suhren Meike, Malik Eduard, Philipsen Alexandra, Müller Helge Ho
Department of Psychiatry and Psychotherapy, Carl von Ossietzky University Oldenburg, Bad Zwischenahn.
Department of Gynecology and Obstetrics, Carl von Ossietzky University Oldenburg, Oldenburg.
Int J Womens Health. 2017 Oct 30;9:795-805. doi: 10.2147/IJWH.S143368. eCollection 2017.
Our aim was to summarize the current relevant literature on concomitant psychiatric symptoms with a focus on anxiety/depression in a population with gynecologic cancer; to identify the predictors, associated factors, and prevention strategies of psychiatric disorders; to examine psychiatric disorders in a population with recurrent gynecologic cancer; and to describe the limitations of the literature and future research areas. Little is known about attending psychiatric disorders in patients with gynecologic and other malignant diseases like cervical or breast cancer. However, patients suffering from other types of gynecologic cancer (eg, genital/cervical cancer) may also have an increased risk of psychiatric symptoms. In this review, we identify the potential information deficits in this field. A two-rater independent literature search was conducted using the PubMed/Google Scholar search engines to systematically evaluate the literature on the research objectives, followed by a critical reflection on the results. Of the 77 screened studies, 15 met the criteria for inclusion in this review. Patients with gynecologic malignancies, especially cervical cancer, had a very high prevalence of psychiatric symptoms including depression (33%-52%). Additionally, the risk groups facing higher rates of concomitant reduced quality of life and increased psychiatric symptoms such as depression were identified. Specifically, low socioeconomic status, sexual inactivity, absence of a partner, and physical symptoms were correlated with an increased risk. Patients suffering from recurrent gynecologic cancer should receive particular attention because of their significantly increased risk of depressive symptoms. Screening programs are needed to detect psychiatric symptoms in cervical cancer patients and the associated high-risk groups. Regular screening should be implemented, and psychosocial care should be provided during follow-up.
我们的目的是总结当前关于妇科癌症患者伴发精神症状（重点为焦虑/抑郁）的相关文献；确定精神障碍的预测因素、相关因素及预防策略；研究复发性妇科癌症患者的精神障碍；并描述文献的局限性及未来研究领域。对于患有妇科及其他恶性疾病（如宫颈癌或乳腺癌）的患者所伴发的精神障碍，我们知之甚少。然而，患有其他类型妇科癌症（如生殖系统/宫颈癌）的患者也可能有更高的精神症状风险。在本综述中，我们确定了该领域潜在的信息不足。我们使用PubMed/谷歌学术搜索引擎进行了双评估者独立文献检索，以系统评价关于研究目标的文献，随后对结果进行批判性反思。在筛选的77项研究中，15项符合纳入本综述的标准。妇科恶性肿瘤患者，尤其是宫颈癌患者，精神症状的患病率非常高，包括抑郁症（33%-52%）。此外，还确定了面临更高伴发生活质量下降和精神症状（如抑郁症）发生率的风险群体。具体而言，社会经济地位低、性活动缺乏、无伴侣以及躯体症状与风险增加相关。患有复发性妇科癌症的患者因其抑郁症状风险显著增加而应受到特别关注。需要开展筛查项目以检测宫颈癌患者及相关高危群体中的精神症状。应实施定期筛查，并在随访期间提供心理社会护理。
