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[人乳头瘤病毒的生殖器外播散性感染:通过人乳头瘤病毒疫苗接种的治疗反应]

[Extragenital, disseminated infection with human papillomaviruses : Therapeutic response through vaccination with HPV].

作者信息

Wiskemann L, Durani B, Hartschuh W

机构信息

Haut- und Laserzentrum Dres. Durani, Bergheimerstr. 56a, 69115, Heidelberg, Deutschland.

Universitäts-Hautklinik, Heidelberg, Deutschland.

出版信息

Hautarzt. 2018 Mar;69(3):245-248. doi: 10.1007/s00105-017-4077-2.

Abstract

A 50-year-old man with widespread manifestation of warts and distinct pruritus for the last 5 years was diagnosed with a reactivated human papillomavirus (HPV) infection by three, genetically verified types (6, 16, 18), which are included in the vaccine Gardasil®. Conventional treatment was not successful, but a rapid and significant reduction of the skin manifestation was observed after vaccination with Gardasil®. To what extent therapy-resistant infections with HPV can be influenced through an active HPV vaccination should be investigated in future trials.

摘要

一名50岁男性,在过去5年中出现广泛的疣表现并伴有明显瘙痒,经基因验证为三种(6型、16型、18型)人乳头瘤病毒(HPV)再激活感染,这些类型都包含在加德西疫苗(Gardasil®)中。传统治疗未成功,但接种加德西疫苗后皮肤表现迅速且显著减轻。未来试验应研究主动接种HPV疫苗对HPV耐药性感染的影响程度。

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