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与HPV 38相关的小腿疣状变应性皮肤炎。

Atopic dermatitis associated with HPV 38 lower leg verrucosis.

作者信息

Slodkowska Elzbieta A, Schwartz Joseph, Rady Peter L, Tyring Stephen K, Carlson J Andrew

机构信息

Division of Dermatopathology, Department of Pathology, Albany Medical College, NY 12208, USA.

出版信息

Am J Dermatopathol. 2010 Aug;32(6):610-3. doi: 10.1097/DAD.0b013e3181cc4176.

Abstract

We describe a 45-year-old woman with atopic dermatitis who presented with a progressive, papular eruption over her anterior lower legs that began 30 years earlier. Biopsy with polymerase chain reaction analysis revealed lichenified plane warts harboring human papillomavirus 38 DNA. No signs or family history of epidermodysplasia verruciformis existed. Local trauma from shaving, barrier dysfunction, and decreased cell immunity and interferon production associated with atopic dermatitis are likely responsible for this presentation of lower leg verrucosis.

摘要

我们描述了一名45岁的特应性皮炎女性患者,其小腿前侧出现进行性丘疹性皮疹,该皮疹始于30年前。聚合酶链反应分析活检显示,苔藓化的扁平疣中含有人类乳头瘤病毒38型DNA。不存在疣状表皮发育不良的体征或家族史。剃须造成的局部创伤、屏障功能障碍以及与特应性皮炎相关的细胞免疫和干扰素产生减少,可能是导致小腿疣状病变的原因。

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