Laboratory of Research in Respiratory Physiotherapy, Department of Physiotherapy, State University of Londrina, Av. Robert Koch, 60 - Vila Operária, Londrina, Parana, 86038-350, Brazil.
Health Sciences Graduate Program, Health Sciences Center, State University of Londrina, Av. Robert Koch, 60 - Vila Operária, Londrina, Parana, 86038-350, Brazil.
Lung. 2018 Feb;196(1):19-26. doi: 10.1007/s00408-017-0068-4. Epub 2017 Nov 13.
To analyze the relationship between oxygen desaturation episodes during a laboratory-based ADL protocol and in real-life routine in patients with stable chronic obstructive pulmonary disease (COPD).
Twenty patients with stable COPD (12 men, 70 ± 7 years, FEV% 54 ± 15 predicted) with no indication for long-term oxygen therapy (LTOT) were submitted to assessments including ADL performance by the Londrina ADL Protocol (LAP) and level of physical activity in daily life, both while submitted to simultaneous activity and pulse oximeter monitoring.
Episodes of desaturation ≥ 4% (ED ≥ 4%) during the LAP were correlated both with ED ≥ 4% in daily life (r = 0.45) and number of episodes of SpO under 88% (ED < 88%) in daily life (r = 0.59). ED < 88% during the LAP was also correlated with ED < 88% in daily life (r = 0.51), explaining 43% of its variance.
In stable patients with COPD and no indication of LTOT, episodes of desaturation during a lab-based ADL protocol are moderately related to episodes of desaturation in daily (real) life, especially those episodes under 88%.
分析稳定期慢性阻塞性肺疾病（COPD）患者在基于实验室的日常生活活动（ADL）方案中发生的氧减饱和事件与日常生活中的真实情况之间的关系。
20 例稳定期 COPD 患者（12 名男性，70 ± 7 岁，FEV%预测值 54 ± 15%）无长期氧疗（LTOT）指征，进行评估包括通过隆德里纳 ADL 方案（LAP）进行 ADL 表现和日常生活中的身体活动水平，同时进行活动和脉搏血氧仪监测。
LAP 中发生的氧减饱和≥4%（ED≥4%）与日常生活中的 ED≥4%（r=0.45）和日常生活中 SpO 低于 88%的事件数（ED<88%）（r=0.59）相关。LAP 中 ED<88%也与日常生活中的 ED<88%相关（r=0.51），解释了其方差的 43%。
在没有 LTOT 指征的稳定期 COPD 患者中，基于实验室的 ADL 方案中发生的氧减饱和事件与日常生活中的氧减饱和事件（真实生活）中度相关，尤其是那些低于 88%的事件。
