Pediatr Infect Dis J. 2018 Mar;37(3):e83-e86. doi: 10.1097/INF.0000000000001826.
Chikungunya virus caused an epidemic on Curaçao in 2014-2015. Infants are highly at risk for clinical syndromes as sepsis-like illness and central nervous system disease. Clinical recognition is important if laboratory test, polymerase chain reaction and enzyme-linked immunosorbent assay are not available. The World Health Organization created criteria for identification of probable Chikungunya virus. None of the studied infants met these criteria. We believe the criteria suggested by World Health Organization should be modified for infants.
基孔肯雅热病毒于 2014-2015 年在库拉索岛引发了一场疫情。婴儿患类似败血症和中枢神经系统疾病等临床综合征的风险很高。如果无法进行实验室检测、聚合酶链反应和酶联免疫吸附试验,则临床识别非常重要。世界卫生组织制定了鉴定可能的基孔肯雅病毒的标准。没有一个研究中的婴儿符合这些标准。我们认为,世界卫生组织建议的标准应针对婴儿进行修改。