婴儿期 2 个月时中枢神经系统中的基孔肯雅病毒的迟发性鉴定：母婴感染的持续性？
Late Identification of Chikungunya Virus in the Central Nervous System of a 2-Month-Old Infant: Persistence of Maternal-Neonatal Infection?
机构信息
Neonatologia, Hospital Universitário Gaffrée e Guinle, Universidade Federal do Estado do Rio de Janeiro, Brazil.
Laboratório de Flavivírus, Instituto Oswaldo Cruz.
出版信息
J Pediatric Infect Dis Soc. 2019 Sep 25;8(4):374-377. doi: 10.1093/jpids/piy135.
We report here a probable case of vertical transmission of chikungunya infection with confirmed maternal viremia close to labor that led to severe infection in the newborn. The newborn progressed with cutaneous lesions and irritability 2 months after vertical transmission, when chikungunya virus was detected in the infant's CSF by a molecular diagnostic test (real-time polymerase chain reaction).
我们在此报告一例可能的基孔肯雅病毒垂直传播感染病例，产妇在临近分娩时存在确证的病毒血症，导致新生儿发生严重感染。新生儿在垂直传播后 2 个月出现皮肤损伤和烦躁不安，通过分子诊断检测（实时聚合酶链反应）在婴儿的脑脊液中检测到基孔肯雅病毒。
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