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Sexual dimorphism and in the aging heart: role of estrogen, nitric oxide and beyond.性二态性与衰老心脏：雌激素、一氧化氮及其他因素的作用
J Mol Cell Cardiol. 2004 Sep;37(3):667-9. doi: 10.1016/j.yjmcc.2004.06.007.
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Does aging cause women to be more sympathetic than men?衰老会使女性比男性更具同情心吗？
Hypertension. 2005 Apr;45(4):489-90. doi: 10.1161/01.HYP.0000160319.33841.ff. Epub 2005 Mar 14.
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[The flicker frequency test in relation to age and sex].[与年龄和性别的闪烁频率测试]
Z Alternsforsch. 1960 Nov;14:318-26.
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The influence of sex and age on uropepsin excretion.性别和年龄对欧洲胃蛋白酶排泄的影响。
Am J Gastroenterol. 1956 Apr;25(4):346-54.
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[Sex differences in the grooming parameters in rat ontogeny].[大鼠个体发育中梳理行为参数的性别差异]
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The 1st World Congress on Gender-Specific Medicine: Men, Women And Medicine. A new view of the biology of sex/gender differences and aging.第一届性别特异性医学世界大会：男性、女性与医学。对性别差异和衰老生物学的新观点。
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Am J Physiol. 1955 Oct;183(1):141-3. doi: 10.1152/ajplegacy.1955.183.1.141.

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Is Sex as a Biological Variable Still Being Ignored in Preclinical Aging Research?性作为生物学变量在临床前衰老研究中是否仍被忽视？
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Age and sex as confounding factors in the relationship between cardiac mitochondrial function and type 2 diabetes in the Nile Grass rat.年龄和性别是 Nile Grass 鼠心脏线粒体功能与 2 型糖尿病之间关系的混杂因素。
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Sex-Specific Responses of Life Span and Fitness to Variation in Developmental Versus Adult Diets in Drosophila melanogaster.性别的特异性对黑腹果蝇的寿命和适应性对发育和成年饮食变化的反应。
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Sex-specific components of frailty in C57BL/6 mice.C57BL/6小鼠衰弱的性别特异性成分
Aging (Albany NY). 2019 Jul 29;11(14):5206-5214. doi: 10.18632/aging.102114.

本文引用的文献

1
Men Sustain Higher Dysregulation Levels Than Women Without Becoming Frail.男性在未变得虚弱前，维持着比女性更高的失调水平。
J Gerontol A Biol Sci Med Sci. 2018 Jan 16;73(2):175-184. doi: 10.1093/gerona/glx146.
2
Sex-dependent Differences in Liver and Gut Metabolomic Profiles With Acarbose and Calorie Restriction in C57BL/6 Mice.性别依赖的差异在肝和肠道代谢组学与阿卡波糖和热量限制在 C57BL/6 小鼠。
J Gerontol A Biol Sci Med Sci. 2018 Jan 16;73(2):157-165. doi: 10.1093/gerona/glx127.
3
Sex Differences in Aging: Genomic Instability.性别与衰老：基因组不稳定性。
J Gerontol A Biol Sci Med Sci. 2018 Jan 16;73(2):166-174. doi: 10.1093/gerona/glx105.
4
Sexual Dimorphism and Aging Differentially Regulate Adaptive Homeostasis.性二态性和衰老对适应性体内平衡的调节存在差异。
J Gerontol A Biol Sci Med Sci. 2018 Jan 16;73(2):141-149. doi: 10.1093/gerona/glx083.
5
Do Female Dogs Age Differently Than Male Dogs?母狗的衰老速度与公狗不同吗？
J Gerontol A Biol Sci Med Sci. 2018 Jan 16;73(2):150-156. doi: 10.1093/gerona/glx061.
6
A randomized controlled trial to establish effects of short-term rapamycin treatment in 24 middle-aged companion dogs.一项随机对照试验，旨在确定短期雷帕霉素治疗对 24 只中年伴侣犬的影响。
Geroscience. 2017 Apr;39(2):117-127. doi: 10.1007/s11357-017-9972-z. Epub 2017 Apr 3.
7
Sex differences in frailty: A systematic review and meta-analysis.衰弱的性别差异：一项系统评价与荟萃分析。
Exp Gerontol. 2017 Mar;89:30-40. doi: 10.1016/j.exger.2016.12.021. Epub 2016 Dec 31.
8
Diet-Microbiome Interactions in Health Are Controlled by Intestinal Nitrogen Source Constraints.饮食-微生物组相互作用在健康中受肠道氮源限制的控制。
Cell Metab. 2017 Jan 10;25(1):140-151. doi: 10.1016/j.cmet.2016.10.021. Epub 2016 Nov 23.
9
Effects of Sex, Strain, and Energy Intake on Hallmarks of Aging in Mice.性别、品系和能量摄入对小鼠衰老特征的影响。
Cell Metab. 2016 Jun 14;23(6):1093-1112. doi: 10.1016/j.cmet.2016.05.027.
10
Sex Differences in Lifespan.寿命的性别差异。
Cell Metab. 2016 Jun 14;23(6):1022-1033. doi: 10.1016/j.cmet.2016.05.019.

Sex and Aging.

作者信息

Le Couteur David G, Anderson Rozalyn M, de Cabo Rafael

机构信息

Centre for Education and Research on Aging, Charles Perkins Centre and ANZAC Research Institute, University of Sydney and Concord Hospital, New South Wales, Australia.

Department of Medicine, University of Wisconsin-Madison GRECC, William S Middleton Memorial Veterans Hospital, Baltimore, Maryland.

出版信息

J Gerontol A Biol Sci Med Sci. 2018 Jan 16;73(2):139-140. doi: 10.1093/gerona/glx221.

DOI:10.1093/gerona/glx221
PMID:29136099
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6279165/
Abstract
摘要