Department of Cardiovascular Surgery, Faculty of Medicine, Heart Center Freiburg University, University of Freiburg, Freiburg, Germany.
Department and Clinic of Cardiac Surgery, Wroclaw Medical University, Wroclaw, Poland.
Eur J Cardiothorac Surg. 2018 Jun 1;53(6):1158-1164. doi: 10.1093/ejcts/ezx379.
The aim of this study was to investigate the accuracy of stent graft deployment in the distal landing zone (LZ) during thoracic endovascular aortic repair (TEVAR). Currently, TEVAR focuses on accurate stent graft deployment in the proximal LZ. Data on landing in the distal LZ are lacking.
Of 195 TEVAR patients (2005-16) with a non-dissected aortic pathology, 59 [median age 73 years (first quartile 68; third quartile 77), 20 women] patients had a distal LZ shorter than 40 mm. In all, the aim was to deploy the stent graft just above the target vessel (coeliac trunk, mesenteric superior or renal artery). Patients were divided into the accurate landing (n = 10) and inaccurate landing (IAL, n = 49) groups according to the distance to the target vessel ≤ 5 mm or > 5 mm after TEVAR, target vessel coverage and the need for a second stent graft in the distal LZ. We assessed the distal LZ, stent graft distance to the target vessel, apposition, migration and endoleak Ib on computed tomography. Median follow-up period was 23 months (5; 48).
Distal LZ anatomy did not differ between groups. Overall stent graft distance to the target vessel was 10.0 mm (6.5 mm; 16.0 mm). Three patients required a second stent graft in the distal LZ, and in 3 others, the target vessel was accidentally covered. In patients of the accurate landing group primary endoleak Ib occurred less frequently than those in the IAL group (0% vs 33%; P = 0.049). Three (30%) accurate landing and 19 (39%) IAL patients (P = 0.73) presented with substantial stent graft wedge apposition.
Accurate stent graft implantation in the distal LZ with the currently available deployment mechanism is often challenging. An inaccurate landing is associated with a higher incidence of endoleak Ib.
本研究旨在探讨胸主动脉腔内修复术(TEVAR)中远端着陆区(LZ)内支架移植物放置的准确性。目前,TEVAR 主要关注近端 LZ 内支架移植物的准确放置。关于远端 LZ 着陆的数据尚缺乏。
在 195 例接受 TEVAR 治疗的非夹层主动脉病变患者(2005-16 年)中,59 例(中位年龄 73 岁[四分位间距 68;77 岁];20 例女性)的远端 LZ 短于 40mm。所有患者的目标均为将支架移植物刚好置于靶血管(腹腔干、肠系膜上动脉或肾动脉)上方。根据 TEVAR 术后至靶血管的距离≤5mm 或>5mm、靶血管覆盖程度以及是否需要在远端 LZ 内放置第二个支架移植物,将患者分为准确着陆(n=10)和不准确着陆(IAL,n=49)两组。我们评估了远端 LZ、支架移植物与靶血管的距离、贴附、迁移和 Ib 型内漏。中位随访时间为 23 个月(5-48 个月)。
两组间远端 LZ 解剖结构无差异。总体而言,支架移植物与靶血管的距离为 10.0mm(6.5mm;16.0mm)。3 例患者需要在远端 LZ 内放置第二个支架移植物,另外 3 例患者靶血管意外被覆盖。在准确着陆组中,原发性 Ib 型内漏的发生率低于 IAL 组(0%比 33%;P=0.049)。3 例(30%)准确着陆患者和 19 例(39%)IAL 患者(P=0.73)出现明显的支架移植物楔形贴附。
在当前可用的释放机制下,准确地在远端 LZ 内植入支架移植物往往具有挑战性。不准确着陆与 Ib 型内漏的发生率较高相关。