Department of Dermatology, Jena University Hospital Erfurter Straße 35, DE-07743 Jena, Germany.
Acta Derm Venereol. 2018 Mar 13;98(3):305-309. doi: 10.2340/00015555-2846.
Scleroedema adultorum Buschke is a rare skin disease, which can be divided into 3 subtypes: classic type, occurring after respiratory infections; a type lacking association with infections; and a type associated with diabetes. Scleroedema adultorum Buschke is characterized by thickening and tightening of the skin, which typically starts at the neck. In half of patients, spontaneous remission may occur. The aim of this systematic review is to summarize all reported treatments for scleroedema adultorum Buschke, based on articles from PubMed database, using the query "scleroedema adultorum Buschke treatment", English and German, published between 1970 and 2016 and documenting adequate treatments. The results are based mainly on individual case reports, small case series, and retrospective studies often reporting unsuccessful results. Treatment options include topical as well as systemic treatments, and physical modalities. There is a need for randomized controlled trials and studies on long-term outcomes after treatment.
成人硬肿病 Buschke 是一种罕见的皮肤疾病，可分为 3 种亚型：经典型，发生于呼吸道感染之后；无感染相关的一型；以及与糖尿病相关的一型。成人硬肿病 Buschke 的特征为皮肤增厚和紧绷，通常从颈部开始。半数患者可能会自发缓解。本系统综述的目的是基于 1970 年至 2016 年间 PubMed 数据库中使用“成人硬肿病 Buschke 治疗”查询词检索到的英文和德文文章，总结所有报道的成人硬肿病 Buschke 的治疗方法，这些文章须有充分的治疗记录。结果主要基于个案报告、小病例系列和回顾性研究，这些研究报告的结果往往并不成功。治疗方法包括局部和全身治疗以及物理疗法。需要进行随机对照试验和治疗后长期结局研究。
