肾细胞癌患者真菌血症的罕见病因：葡萄牙念珠菌血症病例报告
Uncommon cause of fungemia in a patient with renal cell cancer: A case report of Candida lusitaniae Fungemia.
作者信息
Mishra Rashmi, Kelly Paul, Toolsie Omesh, Ayyadurai Puvanalingam, Adrish Muhammad
机构信息
Division of Pulmonary and Critical Care Division of Infectious Diseases Department of Medicine, Bronx-Lebanon Hospital Center, Bronx, NY, USA.
出版信息
Medicine (Baltimore). 2017 Nov;96(45):e8510. doi: 10.1097/MD.0000000000008510.
Abstract
INTRODUCTION
We present an interesting case of Candida lusitaniae infection in a patient diagnosed with renal clear cell carcinoma.An 82-year-old male presented with worsening back pain for 1 week. Physical examination including neurologic examination was normal. A computed tomography scan of the abdomen revealed a mass in the right upper pole of the kidney suggestive of a renal neoplasm. Pathology from a percutaneous biopsy of the kidney revealed clear cell carcinoma. During his hospitalization the patient developed fungemia due to C lusitaniae. He was started on fluconazole, which was later switched to caspofungin due to worsening transaminitis. The patient's clinical status improved and repeat blood cultures were negative for fungal growth.
CONCLUSION
To our knowledge, this is the first case of C lusitaniae reported in a patient diagnosed with clear cell carcinoma of the kidney.
摘要
引言
我们报告一例有趣的光滑念珠菌感染病例，患者被诊断为肾透明细胞癌。一名82岁男性因背痛加重1周前来就诊。包括神经系统检查在内的体格检查均正常。腹部计算机断层扫描显示右肾上极有一个肿块，提示肾肿瘤。经皮肾活检病理显示为透明细胞癌。患者住院期间发生了光滑念珠菌引起的真菌血症。他开始使用氟康唑治疗，后因转氨酶升高恶化而改用卡泊芬净。患者的临床状况有所改善，重复血培养真菌生长呈阴性。
结论
据我们所知，这是首例在诊断为肾透明细胞癌的患者中报告的光滑念珠菌感染病例。
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