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Emerg Infect Dis. 2015 Nov;21(11):1942-50. doi: 10.3201/eid2111.150404.
2
Acquired Multidrug Antifungal Resistance in Candida lusitaniae during Therapy.治疗期间葡萄牙念珠菌获得性多重耐药
Antimicrob Agents Chemother. 2015 Dec;59(12):7715-22. doi: 10.1128/AAC.02204-15. Epub 2015 Oct 5.
3
Epidemiology and outcomes of invasive candidiasis due to non-albicans species of Candida in 2,496 patients: data from the Prospective Antifungal Therapy (PATH) registry 2004-2008.2496例非白色念珠菌所致侵袭性念珠菌病的流行病学及转归：来自2004 - 2008年前瞻性抗真菌治疗（PATH）注册研究的数据
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4
Species identification and antifungal susceptibility testing of Candida bloodstream isolates from population-based surveillance studies in two U.S. cities from 2008 to 2011.2008 年至 2011 年，在美国两个城市进行的基于人群的监测研究中，从血流感染分离株中进行的念珠菌种鉴定和抗真菌药敏试验。
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Development of echinocandin resistance in Clavispora lusitaniae during caspofungin treatment.在卡泊芬净治疗期间，光滑球拟酵母菌产生棘白菌素类耐药性。
J Clin Microbiol. 2011 Jun;49(6):2304-6. doi: 10.1128/JCM.00325-11. Epub 2011 Apr 13.
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10
Nosocomial breakthrough fungaemia during antifungal prophylaxis or empirical antifungal therapy in 41 cancer patients receiving antineoplastic chemotherapy: analysis of aetiology risk factors and outcome.41例接受抗肿瘤化疗的癌症患者在抗真菌预防或经验性抗真菌治疗期间发生的医院获得性突破性真菌血症：病因、危险因素及预后分析
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肾细胞癌患者真菌血症的罕见病因：葡萄牙念珠菌血症病例报告

Uncommon cause of fungemia in a patient with renal cell cancer: A case report of Candida lusitaniae Fungemia.

作者信息

Mishra Rashmi, Kelly Paul, Toolsie Omesh, Ayyadurai Puvanalingam, Adrish Muhammad

机构信息

Division of Pulmonary and Critical Care Division of Infectious Diseases Department of Medicine, Bronx-Lebanon Hospital Center, Bronx, NY, USA.

出版信息

Medicine (Baltimore). 2017 Nov;96(45):e8510. doi: 10.1097/MD.0000000000008510.

DOI:10.1097/MD.0000000000008510
PMID:29137050
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5690743/
Abstract

INTRODUCTION

We present an interesting case of Candida lusitaniae infection in a patient diagnosed with renal clear cell carcinoma.An 82-year-old male presented with worsening back pain for 1 week. Physical examination including neurologic examination was normal. A computed tomography scan of the abdomen revealed a mass in the right upper pole of the kidney suggestive of a renal neoplasm. Pathology from a percutaneous biopsy of the kidney revealed clear cell carcinoma. During his hospitalization the patient developed fungemia due to C lusitaniae. He was started on fluconazole, which was later switched to caspofungin due to worsening transaminitis. The patient's clinical status improved and repeat blood cultures were negative for fungal growth.

CONCLUSION

To our knowledge, this is the first case of C lusitaniae reported in a patient diagnosed with clear cell carcinoma of the kidney.

摘要

引言

我们报告一例有趣的光滑念珠菌感染病例，患者被诊断为肾透明细胞癌。一名82岁男性因背痛加重1周前来就诊。包括神经系统检查在内的体格检查均正常。腹部计算机断层扫描显示右肾上极有一个肿块，提示肾肿瘤。经皮肾活检病理显示为透明细胞癌。患者住院期间发生了光滑念珠菌引起的真菌血症。他开始使用氟康唑治疗，后因转氨酶升高恶化而改用卡泊芬净。患者的临床状况有所改善，重复血培养真菌生长呈阴性。

结论

据我们所知，这是首例在诊断为肾透明细胞癌的患者中报告的光滑念珠菌感染病例。