Girmenia Corrado, Moleti Maria Luisa, Micozzi Alessandra, Iori Anna Paola, Barberi Walter, Foà Robin, Martino Pietro
Dipartimento di Biotecnologie Cellulari ed Ematologia, University "La Sapienza," Rome 00161, Italy.
J Clin Microbiol. 2005 Oct;43(10):5395-6. doi: 10.1128/JCM.43.10.5395-5396.2005.
We report a case of breakthrough invasive zygomycosis in a stem cell transplant recipient who was receiving caspofungin for treatment of a breakthrough Candida krusei fungemia that occurred during fluconazole prophylaxis. Also, patients receiving the echinocandin caspofungin remain at risk for pathogens, such as zygomycetes, that are intrinsically resistant to this agent.
我们报告了一例干细胞移植受者发生突破性侵袭性接合菌病的病例,该患者在接受氟康唑预防治疗期间发生了突破性克柔念珠菌血症,正在接受卡泊芬净治疗。此外,接受棘白菌素类药物卡泊芬净治疗的患者,对于诸如接合菌这类对该药物天然耐药的病原体,仍有感染风险。