Highly Efficacious Novel Vaccine, Humoral Immunity, and Ocular Herpes Simplex Virus 1: Reality or Myth?
作者信息
Ghiasi Homayon
机构信息
Center for Neurobiology and Vaccine Development, Ophthalmology Research, Department of Surgery, Cedars-Sinai Burns & Allen Research Institute, Los Angeles, California, USA
出版信息
J Virol. 2017 Nov 14;91(23). doi: 10.1128/JVI.01421-17. Print 2017 Dec 1.
Abstract
摘要
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本文引用的文献
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The Neonatal Fc Receptor and Complement Fixation Facilitate Prophylactic Vaccine-Mediated Humoral Protection against Viral Infection in the Ocular Mucosa.新生儿Fc受体与补体固定作用促进预防性疫苗介导的眼黏膜体液免疫以抵御病毒感染。
J Immunol. 2017 Sep 1;199(5):1898-1911. doi: 10.4049/jimmunol.1700316. Epub 2017 Jul 31.
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A Highly Efficacious Herpes Simplex Virus 1 Vaccine Blocks Viral Pathogenesis and Prevents Corneal Immunopathology via Humoral Immunity.一种高效的单纯疱疹病毒1型疫苗可通过体液免疫阻断病毒发病机制并预防角膜免疫病理。
J Virol. 2016 May 12;90(11):5514-5529. doi: 10.1128/JVI.00517-16. Print 2016 Jun 1.
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Efficacy results of a trial of a herpes simplex vaccine.一项单纯疱疹疫苗试验的疗效结果。
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VACCINE THERAPY IN RECURRENT HERPES SIMPLEX.复发性单纯疱疹的疫苗治疗
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Glycoprotein-D-adjuvant vaccine to prevent genital herpes.用于预防生殖器疱疹的糖蛋白-D佐剂疫苗。
N Engl J Med. 2002 Nov 21;347(21):1652-61. doi: 10.1056/NEJMoa011915.
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Prospects for control of herpes simplex virus disease through immunization.通过免疫接种控制单纯疱疹病毒疾病的前景。
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High frequency of CD8+ cytotoxic T-lymphocyte precursors specific for herpes simplex viruses in persons with genital herpes.生殖器疱疹患者中针对单纯疱疹病毒的CD8 + 细胞毒性T淋巴细胞前体的高频率
J Virol. 1996 Nov;70(11):8165-8. doi: 10.1128/JVI.70.11.8165-8168.1996.
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Passive transfer of anti-herpes simplex virus type 2 monoclonal and polyclonal antibodies protect against herpes simplex virus type 1-induced but not herpes simplex virus type 2-induced stromal keratitis.抗单纯疱疹病毒2型单克隆抗体和多克隆抗体的被动转移可预防单纯疱疹病毒1型诱发的基质性角膜炎，但不能预防单纯疱疹病毒2型诱发的基质性角膜炎。
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Expression of seven herpes simplex virus type 1 glycoproteins (gB, gC, gD, gE, gG, gH, and gI): comparative protection against lethal challenge in mice.七种1型单纯疱疹病毒糖蛋白（gB、gC、gD、gE、gG、gH和gI）的表达：小鼠致死性攻击的比较保护作用
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Vaccine therapy for ocular herpes simplex virus (HSV) infection: periocular vaccination reduces spontaneous ocular HSV type 1 shedding in latently infected rabbits.眼部单纯疱疹病毒（HSV）感染的疫苗治疗：眼周接种疫苗可减少潜伏感染兔的自发性眼部1型HSV脱落。
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