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慢性阻塞性肺疾病患者中的电子烟:当前观点

E-cigarettes in patients with COPD: current perspectives.

作者信息

Morjaria J B, Mondati E, Polosa R

机构信息

Department of Respiratory Medicine, Royal Brompton and Harefield Hospital Foundation Trust, Harefield Hospital, Harefield.

Department of Respiratory Medicine, Imperial College, London, UK.

出版信息

Int J Chron Obstruct Pulmon Dis. 2017 Nov 1;12:3203-3210. doi: 10.2147/COPD.S135323. eCollection 2017.

DOI:10.2147/COPD.S135323
PMID:29138548
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5677304/
Abstract

Conventional cigarette smoking is known to result in significant COPD morbidity and mortality. Strategies to reduce and/or stop smoking in this highly vulnerable patient group are key public health priorities to reduce COPD morbidity and mortality. Unfortunately, smoking cessation efforts in patients with COPD are poor and there is a compelling need for more efficient approaches to cessation for patients with COPD. Electronic cigarettes (ECs) are devices that use batteries to vaporize nicotine. They may facilitate quit attempts and cessation in many smokers. Although they are not risk free, ECs are much less harmful than tobacco smoking. Hence, the use of ECs in vulnerable groups and in patients with challenges to abstain or multiple relapses to this habit may be promising. To date, little is known about health consequences of EC use among COPD smokers and whether their regular use has any effects on subjective and objective COPD outcomes. In the current review, we discuss the current perspectives and literature on the role of ECs in abstaining from conventional smoking and the effects of ECs on the respiratory tract in patients with COPD.

摘要

众所周知,传统香烟吸烟会导致严重的慢性阻塞性肺疾病(COPD)发病和死亡。在这个高度脆弱的患者群体中减少和/或戒烟的策略是降低COPD发病率和死亡率的关键公共卫生优先事项。不幸的是,COPD患者的戒烟努力效果不佳,迫切需要更有效的戒烟方法来帮助COPD患者。电子烟(ECs)是使用电池将尼古丁汽化的装置。它们可能有助于许多吸烟者尝试戒烟和成功戒烟。虽然电子烟并非没有风险,但比吸烟危害小得多。因此,在弱势群体以及难以戒除或多次复吸的患者中使用电子烟可能是有前景的。迄今为止,关于COPD吸烟者使用电子烟的健康后果以及其长期使用是否对COPD的主观和客观结果有任何影响,人们知之甚少。在当前的综述中,我们讨论了关于电子烟在戒除传统吸烟方面的作用以及电子烟对COPD患者呼吸道影响的当前观点和文献。

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Variable Susceptibility to Cigarette Smoke-Induced Emphysema in 34 Inbred Strains of Mice Implicates Abi3bp in Emphysema Susceptibility.34个近交系小鼠对香烟烟雾诱导的肺气肿易感性存在差异,提示Abi3bp与肺气肿易感性有关。
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