Litt Mark D, Duffy Valerie, Oncken Cheryl
University of Connecticut Health Center, Farmington, Connecticut, USA.
University of Connecticut, Storrs, Connecticut, USA.
Tob Control. 2016 Nov;25(Suppl 2):ii67-ii72. doi: 10.1136/tobaccocontrol-2016-053223. Epub 2016 Sep 15.
The present study examined the influence of flavouring on the smoking and vaping behaviour of cigarette smokers asked to adopt e-cigarettes for a period of 6 weeks.
Participants were 88 current male and female smokers with no intention to stop smoking, but who agreed to substitute e-cigarettes for their current cigarettes. On intake, participants were administered tests of taste and smell for e-cigarettes flavoured with tobacco, menthol, cherry and chocolate, and were given a refillable e-cigarette of their preferred flavour or a control flavour. Participants completed daily logs of cigarette and e-cigarette use and were followed each week.
Analyses over days indicated that, during the 6-week e-cigarette period, cigarette smoking rates dropped from an average of about 16 to about 7 cigarettes/day. e-Cigarette flavour had a significant effect such that the largest drop in cigarette smoking occurred among those assigned menthol e-cigarettes, and the smallest drop in smoking occurred among those assigned chocolate and cherry flavours. e-Cigarette vaping rates also differed significantly by flavour assigned, with the highest vaping rates for tobacco- and cherry-flavoured e-cigarettes, and the lowest rates for those assigned to chocolate.
The findings suggest that adoption of e-cigarettes in smokers may influence smoking rates and that e-cigarette flavourings can moderate this effect. e-Cigarette vaping rates are also influenced by flavourings. These findings may have implications for the utility of e-cigarettes as a nicotine replacement device and for the regulation of flavourings in e-cigarettes for harm reduction.
本研究调查了调味剂对被要求使用电子烟六周的吸烟者吸烟及吸电子烟行为的影响。
参与者为88名当前仍在吸烟的男性和女性,他们无意戒烟,但同意用电子烟替代当前所吸的香烟。在纳入研究时,对参与者进行了针对烟草味、薄荷味、樱桃味和巧克力味电子烟的味觉和嗅觉测试,并给他们一支可再填充的其偏好口味或对照口味的电子烟。参与者完成每日吸烟及吸电子烟记录,且每周接受随访。
按天数进行的分析表明,在为期六周的电子烟使用期内,吸烟率从平均每天约16支降至约7支。电子烟口味有显著影响,即分配到薄荷味电子烟的参与者吸烟量下降幅度最大,而分配到巧克力味和樱桃味电子烟的参与者吸烟量下降幅度最小。吸电子烟的比率也因所分配的口味而有显著差异,烟草味和樱桃味电子烟的吸用率最高,而分配到巧克力味电子烟的吸用率最低。
研究结果表明,吸烟者采用电子烟可能会影响吸烟率,且电子烟调味剂可调节这种影响。吸电子烟的比率也受调味剂影响。这些发现可能对电子烟作为尼古丁替代装置的效用以及电子烟调味剂用于减少危害的监管有影响。