Department of Obstetrics and Gynecology, NKP Salve Institute of Medical Sciences, Nagpur, India.
Int J Gynaecol Obstet. 2018 May;141(2):217-221. doi: 10.1002/ijgo.12388. Epub 2017 Dec 13.
To assess the feasibility of the PALM-COEIN system for the classification of abnormal uterine bleeding (AUB) in low-resource settings and to suggest modifications.
A prospective study was conducted among women with AUB who were admitted to the gynecology ward of a tertiary care hospital and research center in central India between November 2014 and October 2016. All patients were managed as per department protocols. The causes of AUB were classified before treatment using the PALM-COEIN system (classification I) and on the basis of the histopathology reports of the hysterectomy specimens (classification II); the results were compared using classification II as the gold standard.
The study included 200 women with AUB; hysterectomy was performed in 174 women. Preoperative classification of AUB per the PALM-COEIN system was correct in 130 (65.0%) women. Adenomyosis (evaluated by transvaginal ultrasonography) and endometrial hyperplasia (evaluated by endometrial curettage) were underdiagnosed.
The PALM-COEIN classification system helps in deciding the best treatment modality for women with AUB on a case-by-case basis. The incorporation of suggested modifications will further strengthen its utility as a pretreatment classification system in low-resource settings.
评估 PALM-COEIN 系统在资源匮乏环境下对异常子宫出血(AUB)进行分类的可行性,并提出修改建议。
本前瞻性研究纳入了 2014 年 11 月至 2016 年 10 月期间在印度中部一家三级保健医院和研究中心妇科病房就诊的 AUB 女性患者。所有患者均按照科室方案进行治疗。采用 PALM-COEIN 系统(分类 I)在治疗前对 AUB 的病因进行分类,并根据子宫切除术标本的组织病理学报告(分类 II)进行分类;以分类 II 作为金标准比较两种分类方法的结果。
本研究共纳入 200 例 AUB 患者,其中 174 例行子宫切除术。根据 PALM-COEIN 系统对 AUB 的术前分类在 130 例(65.0%)患者中是正确的。子宫腺肌病(经阴道超声检查评估)和子宫内膜增生(经子宫内膜刮宫术评估)被漏诊。
PALM-COEIN 分类系统有助于根据具体情况为 AUB 患者决定最佳治疗方法。纳入这些修改建议将进一步增强其在资源匮乏环境下作为预处理分类系统的实用性。