Kolafová Martina, Šťovíček Jan, Strnad Jakub, Zemek Josef, Dybal Jiři
Int J Oral Maxillofac Implants. 2017 Nov/Dec;32(6):1221-1230. doi: 10.11607/jomi.5132.
The goal of this study was to compare the in vitro bioactivity in simulated body fluid (SBF) of commercially available dental implants.
Bioactivity, according to ISO 23317, of commercially available dental implants with various surface modifications (BIO-surface, SLA, SLActive, TiUnite, and OsseoSpeed) was tested in SBF for 1 and 3 weeks. Surface characterizations, especially calcium and phosphorus surface content before and after the immersion in SBF, were performed. The effect of surface treatment on bioactivity was studied.
Differences between surfaces before immersion in SBF were confirmed by Raman spectroscopy, x-ray photoelectron spectroscopy (XPS), energy-dispersive x-ray spectroscopy (EDX), and scanning electron microscope (SEM) analysis. Calcium and phosphorus surface content was increasing within the tested period in the case of two (BIO-surface and SLActive) of the five tested dental implants. Calcium-phosphate precipitation was observed by SEM, XPS, EDX, and x-ray micro‑diffraction (μ-XRD) analysis.
Two (BIO-surface from LASAK and SLActive from Straumann) of the five tested dental implants were found to be bioactive, according to ISO 23317. Although it is difficult to unambiguously determine the properties that have influence on the hydroxyapatite precipitation rate, multiple properties that the two surfaces have in common were found.
本研究的目的是比较市售牙科植入物在模拟体液（SBF）中的体外生物活性。
根据ISO 23317，对具有各种表面改性（生物表面、SLA、SLActive、TiUnite和OsseoSpeed）的市售牙科植入物在SBF中进行1周和3周的生物活性测试。进行了表面表征，特别是在SBF中浸泡前后的钙和磷表面含量。研究了表面处理对生物活性的影响。
通过拉曼光谱、X射线光电子能谱（XPS）、能量色散X射线光谱（EDX）和扫描电子显微镜（SEM）分析证实了在SBF中浸泡前各表面之间的差异。在五种测试牙科植入物中的两种（生物表面和SLActive）中，钙和磷表面含量在测试期间有所增加。通过SEM、XPS、EDX和X射线微衍射（μ-XRD）分析观察到磷酸钙沉淀。
根据ISO 23317，在五种测试牙科植入物中，发现两种（来自LASAK的生物表面和来自Straumann的SLActive）具有生物活性。尽管难以明确确定对羟基磷灰石沉淀速率有影响的特性，但发现了这两种表面共有的多种特性。
