Medicine and Surgery Program, PhD School, University of the Basque Country UPV/EHU, Leioa, 48940 Bizkaia, Spain.
Maxillofacial Group, Stomatology Department, BioCruces Health Research Institute, University of the Basque Country UPV/EHU, Leioa, 48940 Bizkaia, Spain.
Int J Mol Sci. 2021 Mar 5;22(5):2597. doi: 10.3390/ijms22052597.
Organic contaminants significantly limit the bioactivity of titanium implants, resulting in the degradation known as the ageing of titanium. To reactivate the surfaces, they can be photofunctionalized, i.e., irradiated with C-range ultraviolet (UVC) light. This descriptive in vitro study compares the effectiveness of novel light-emitting diode (LED) technology to remove contaminant hydrocarbons from three different commercially available titanium dental implants: THD, TiUnite, and SLA. The surface topography and morphology were characterized by scanning electron microscopy (SEM). The chemical compositions were analyzed by X-ray photoelectron spectroscopy (XPS), before and after the lighting treatment, by a pair of closely placed UVC (λ = 278 nm) and LED devices for 24 h. SEM analysis showed morphological differences at the macro- and micro-scopic level. XPS analysis showed a remarkable reduction in the carbon contents after the UVC treatment: from 25.6 to 19.5 C at. % (carbon atomic concentration) in the THD; from 30.2 to 20.2 C at. % in the TiUnite; from 26.1 to 19.2 C at. % in the SLA surface. Simultaneously, the concentration of oxygen and titanium increased. Therefore, LED-based UVC irradiation decontaminated titanium surfaces and improved the chemical features of them, regardless of the kind of surface.
有机污染物会显著限制钛植入物的生物活性，导致钛的老化降解。为了重新激活表面，可以对其进行光功能化处理，即用 C 波段的紫外线（UVC）光照射。本描述性体外研究比较了新型发光二极管（LED）技术对三种不同市售钛牙科植入物（THD、TiUnite 和 SLA）表面去除污染物碳氢化合物的效果。通过扫描电子显微镜（SEM）对表面形貌和形态进行了表征。用一对紧密放置的 UVC（λ=278nm）和 LED 设备进行 24 小时照射处理前后，用 X 射线光电子能谱（XPS）分析了化学成分。SEM 分析显示宏观和微观水平的形态差异。XPS 分析表明，UVC 处理后碳含量显著降低：THD 从 25.6 降至 19.5 at.%（碳原子浓度）；TiUnite 从 30.2 降至 20.2 at.%；SLA 表面从 26.1 降至 19.2 at.%。同时，氧和钛的浓度增加。因此，基于 LED 的 UVC 辐照可去除钛表面的污染物，并改善其化学特性，无论表面类型如何。
