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[成年小鼠胚胎肝脏和骨髓中集落形成单位两个亚群亚致死性辐射损伤的细胞修复]

[Cellular repair of sublethal radiation damage in 2 subpopulations of the CFUs from embryonal liver and bone marrow of adult mice].

作者信息

Gan O I, Todriia T V

出版信息

Biull Eksp Biol Med. 1989 Jan;107(1):89-91.

PMID:2914181
Abstract

The authors studied the ability of the CFU-s, forming colonies on the 8 and 11 day after transplantation of cells from fetal liver (FL) of 14-18 day gestation and adult mouse bone marrow (BM), to repair the sublethal radiation damages (SRD), according to Elkind's model. The ability to repair the SRD of 11-day CFU-s (both EL- and BM-derived) was lower than the ability of 8-day CFU-s. Both subpopulations of CFU-s (as 8-, as 11-day) from FL have a reduced index of SRD reparation as compared with the corresponding meanings for BM.

摘要

作者根据埃尔金德模型,研究了移植妊娠14 - 18天胎儿肝脏(FL)和成年小鼠骨髓(BM)细胞后第8天和第11天形成集落的脾集落形成单位(CFU - s)修复亚致死性辐射损伤(SRD)的能力。11天CFU - s(源自EL和BM)修复SRD的能力低于8天CFU - s。与BM的相应数值相比,来自FL的CFU - s的两个亚群(8天和11天的)SRD修复指数均降低。

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