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[小鼠胚胎肝脏造血干细胞辐射损伤的修复。动力学方面]

[Repair of the radiation damage in hematopoietic stem cells from the mouse embryonic liver. Kinetic aspects].

作者信息

Gan O I, Todriia T V

出版信息

Radiobiologiia. 1991 Mar-Apr;31(2):222-6.

PMID:1674612
Abstract

The method of fractionated irradiation was used to study kinetic aspects of repair of sublethal radiation damages in precursor cells from mouse embryonal liver that form in vivo colonies on 8th and 11th days. It was shown that 11-day CFUs had a lesser ability to repair sublethal radiation damages than 8-day ones at different time-intervals between radiation fractions (from 2 to 6 h). These two CFUs sub-populations differed also in the repair kinetics.

摘要

采用分次照射法研究了来自小鼠胚胎肝脏的前体细胞中亚致死性辐射损伤修复的动力学方面,这些前体细胞在第8天和第11天在体内形成集落。结果表明,在分次照射之间的不同时间间隔(2至6小时),11天的集落形成单位(CFU)修复亚致死性辐射损伤的能力低于8天的CFU。这两个CFU亚群在修复动力学方面也存在差异。

相似文献

1
[Repair of the radiation damage in hematopoietic stem cells from the mouse embryonic liver. Kinetic aspects].[小鼠胚胎肝脏造血干细胞辐射损伤的修复。动力学方面]
Radiobiologiia. 1991 Mar-Apr;31(2):222-6.
2
[Comparison of the reparative property of early and late CFUs after sublethal radiation injury].[亚致死性辐射损伤后早期和晚期集落形成单位修复特性的比较]
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[Characteristics of mouse hematopoietic stem cells in the phase of enhanced radioresistance after sublethal irradiation].[亚致死剂量照射后小鼠造血干细胞抗辐射能力增强阶段的特征]
Radiobiologiia. 1989 Mar-Apr;29(2):266-8.
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[Histological study of splenic colonies at different times following the transplantation of hematopoietic cells from embryonic liver].[胚胎肝造血细胞移植后不同时间脾集落的组织学研究]
Ontogenez. 1988 Jul-Aug;19(4):380-4.
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[Effect of the dose of injected hematopoietic cells on the number of daughter splenic colony-forming cells in spleen colonies].[注射造血细胞剂量对脾集落中脾集落形成细胞子代数量的影响]
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