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通过营养不良-炎症评分评估腹膜透析患者的营养不良严重程度

Assessment of Severity of Malnutrition in Peritoneal Dialysis Patients via Malnutrition: Inflammatory Score.

作者信息

Naeeni Afsoon Emami, Poostiyan Nazila, Teimouri Zahra, Mortazavi Mojgan, Soghrati Mojgan, Poostiyan Elnaz, Paknahad Zamzam

机构信息

Isfahan Kidney Diseases Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.

Department of Dermatology, Isfahan University of Medical Sciences, Isfahan, Iran.

出版信息

Adv Biomed Res. 2017 Oct 16;6:128. doi: 10.4103/abr.abr_554_13. eCollection 2017.

Abstract

BACKGROUND

Regarding to the complications of malnutrition in dialysis patients, using an easy and reliable method for evaluating of malnutrition is important in patients with the end-stage renal disease. Based on the effect of inflammatory factors in malnutrition, A new scale has been designed which is called malnutrition-inflammatory scale (MIS). We designed current study to assess the severity of malnutrition in peritoneal dialysis patients in Isfahan via MIS.

MATERIALS AND METHODS

In this cross-sectional MIS was used for evaluation of malnutrition. MIS includes 10 components: dry weight changes, dietary intake, functional capacity, comorbidity, muscle wasting and loss of subcutaneous fat as well as body mass index (BMI), serum albumin level and total iron binding capacity (TIBC). Each component has four levels of severity from 0 (normal) to 3 (severely abnormal). All analyses were performed using Statistical Package for Social Sciences version 20 (SPSS 20) and < 0.05 were considered statistically significant.

RESULTS

Results showed no significant difference in MIS between male and female participants. Mean of minimum inhibitory concentration in this study was calculated about 4.1 (MIS <9) which means no or mild malnutrition. Significant correlation between MIS and weight ( < 0.001), BMI ( < 0.001), TIBC ( < 0.001), triglyseride ( = 0.04) and arm circumference ( < 0.001) was seen.

CONCLUSION

We suggest That MIS is being used as a valuable tool for prevention of fatal outcomes in chronic dialysis patients.

摘要

背景

关于透析患者营养不良的并发症,采用一种简单可靠的方法评估终末期肾病患者的营养不良情况很重要。基于炎症因子在营养不良中的作用,设计了一种新的量表,称为营养不良-炎症量表(MIS)。我们开展本研究以通过MIS评估伊斯法罕腹膜透析患者的营养不良严重程度。

材料与方法

在这项横断面研究中,使用MIS评估营养不良情况。MIS包括10个组成部分:干体重变化、饮食摄入、功能能力、合并症、肌肉萎缩和皮下脂肪丢失以及体重指数(BMI)、血清白蛋白水平和总铁结合力(TIBC)。每个组成部分有从0(正常)到3(严重异常)四个严重程度级别。所有分析均使用社会科学统计软件包第20版(SPSS 20)进行,P<0.05被认为具有统计学意义。

结果

结果显示男性和女性参与者的MIS无显著差异。本研究中最小抑菌浓度的平均值约为4.1(MIS<9),这意味着无营养不良或轻度营养不良。观察到MIS与体重(P<0.001)、BMI(P<0.001)、TIBC(P<0.001)、甘油三酯(P = 0.04)和臂围(P<0.001)之间存在显著相关性。

结论

我们建议将MIS用作预防慢性透析患者致命结局的有价值工具。

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