Schiller V, Aberle D R, Aberle A M
Department of Radiological Sciences, University of California Los Angeles School of Medicine.
Chest. 1989 Feb;95(2):466-7. doi: 10.1378/chest.95.2.466.
Pulmonary alveolar proteinosis is characterized by excessive accumulation of surfactant-like material in the alveoli, resulting in part from defective alveolar clearance by macrophages. We present a case of alveolar proteinosis in a patient with malignant melanoma metastatic to lung and discuss possible alteration in macrophage function in the pathogenesis of these two concomitant processes.
肺泡蛋白沉积症的特征是肺泡内出现过多类似表面活性剂的物质堆积，部分原因是巨噬细胞对肺泡的清除功能存在缺陷。我们报告了一例恶性黑色素瘤肺转移患者发生肺泡蛋白沉积症的病例，并讨论了在这两个并发过程的发病机制中巨噬细胞功能可能发生的改变。
