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冷冻溶脂术后的矛盾性脂肪增生(PAH)

Paradoxical Adipose Hypertrophy (PAH) After Cryolipolysis.

作者信息

Stroumza Nathaniel, Gauthier Nelly, Senet Patricia, Moguelet Philippe, Nail Barthelemy Raphael, Atlan Michael

机构信息

Surgical Attending Physicians in Plastic Surgery.

private practitioner in Paris, France.

出版信息

Aesthet Surg J. 2018 Mar 14;38(4):411-417. doi: 10.1093/asj/sjx159.

Abstract

BACKGROUND

Cryolipolysis is a minimally invasive technique used to decrease local adipose tissue by thermal cooling. Paradoxical adipose hypertrophy (PAH) is a rare complication of cryolipolysis with important aesthetic consequences.

OBJECTIVES

The objective of this study was to describe four cases of PAH after a cryolipolysis treatment.

METHODS

Between January 2014 and January 2017, all patients who had undergone a cryolipolysis treatment in a single center were reviewed. The device used was a CoolSculpting device and the same operator performed all the cryolipolysis treatments. We retrospectively included all patients who had a suspicion of PAH.

RESULTS

In our study, 398 patients underwent a session of cryolipolysis. Four patients presented with a voluminous painless swelling in the treated area, between 2 and 4 months after the cryolipolysis session. One patient was treated with liposuction. Histological analysis of the adipose tissue in this patient revealed a nonspecific panniculitis. The other three patients did not receive any additional treatment, and their symptoms stabilized after several months.

CONCLUSIONS

Although cryolipolysis generally yields good results, it can be complicated with PAH, which tends to occur a few months after the cryolipolysis treatment. Patients should be informed of the possibility of developing this complication and encouraged to attend regular follow up for at least 6 months, so that this condition can be readily detected. Surgical treatment should be offered if there is no spontaneous improvement of the symptoms.

摘要

背景

冷冻溶脂术是一种通过热冷却来减少局部脂肪组织的微创技术。反常性脂肪增生(PAH)是冷冻溶脂术的一种罕见并发症,具有重要的美学影响。

目的

本研究的目的是描述4例冷冻溶脂治疗后发生PAH的病例。

方法

回顾2014年1月至2017年1月在单一中心接受冷冻溶脂治疗的所有患者。使用的设备是酷塑设备,且所有冷冻溶脂治疗均由同一名操作人员进行。我们回顾性纳入了所有疑似PAH的患者。

结果

在我们的研究中,398例患者接受了一次冷冻溶脂治疗。4例患者在冷冻溶脂治疗后2至4个月,治疗区域出现无痛性肿大。1例患者接受了抽脂治疗。对该患者脂肪组织的组织学分析显示为非特异性脂膜炎。其他3例患者未接受任何额外治疗,其症状在数月后稳定。

结论

尽管冷冻溶脂术通常能取得良好效果,但可能并发PAH,PAH往往发生在冷冻溶脂治疗后的几个月。应告知患者发生这种并发症的可能性,并鼓励他们至少定期随访6个月,以便能及时发现这种情况。如果症状没有自发改善,应提供手术治疗。

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