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交界性叶状肿瘤内的原位及浸润性导管癌

In Situ and Invasive Ductal Carcinoma Within a Borderline Phyllodes Tumor.

作者信息

Trabelsi Amel, Abdelkrim Soumaya Ben, Stita Wided, Boudagga Mohamed Zaher, Hammedi Faten, Mokni Moncef

机构信息

Department of Pathology, Farhat Hached Hospital, Sousse, Tunisia.

Department of Medical Oncology, Farhat Hached Hospital, Sousse, Tunisia.

出版信息

World J Oncol. 2010 Feb;1(1):42-44. doi: 10.4021/wjon2010.01.1203. Epub 2010 Feb 1.

DOI:10.4021/wjon2010.01.1203
PMID:29147178
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5649733/
Abstract

A rare case of a borderline phyllodes tumor with simultaneous intraductal and infiltrating duct carcinoma is reported. The patient was a 52-year-old woman with a breast tumor detected by physical examination. A simple mastectomy was performed. The excised tumor had a macroscopic appearance of a phyllodes tumor. After histological examination, the diagnosis of ductal carcinoma within a borderline phyllodes tumor was made. Immunohistochemical staining revealed that the epithelial component was positive for Epithelial Membrane Antigen and cytokeratin. No metastasis was detected in the axillary lymph nodes and the patient didn't receive any adjuvant therapy. No recurrence or metastasis has been observed 38 months after the surgery.

摘要

报道了一例罕见的交界性叶状肿瘤同时合并导管内癌和浸润性导管癌的病例。患者为一名52岁女性,通过体格检查发现乳腺肿瘤。实施了单纯乳房切除术。切除的肿瘤在大体上表现为叶状肿瘤。经组织学检查,诊断为交界性叶状肿瘤内的导管癌。免疫组织化学染色显示上皮成分上皮膜抗原和细胞角蛋白呈阳性。腋窝淋巴结未检测到转移,患者未接受任何辅助治疗。术后38个月未观察到复发或转移。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6921/5649733/a0f416e1c9db/wjon-01-042-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6921/5649733/a0f416e1c9db/wjon-01-042-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6921/5649733/a0f416e1c9db/wjon-01-042-g001.jpg

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本文引用的文献

1
Malignant phyllodes tumour with intraductal and invasive carcinoma and lymph node metastasis.伴有导管内癌、浸润性癌及淋巴结转移的恶性叶状肿瘤
Singapore Med J. 2008 Nov;49(11):e318-21.
2
A case of noninvasive ductal carcinoma arising in malignant phyllodes tumor.1例起源于恶性叶状肿瘤的非浸润性导管癌。
Breast Cancer. 2006;13(1):89-94. doi: 10.2325/jbcs.13.89.
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In-situ and invasive carcinoma within a phyllodes tumor associated with lymph node metastases.叶状肿瘤内原位癌及浸润癌伴淋巴结转移。
World J Surg Oncol. 2004 Dec 15;2:46. doi: 10.1186/1477-7819-2-46.
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Virchows Arch. 1998 Jan;432(1):89-93. doi: 10.1007/s004280050139.
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Cancer. 1980 Oct 15;46(8):1863-7. doi: 10.1002/1097-0142(19801015)46:8<1863::aid-cncr2820460826>3.0.co;2-1.