Leong A S, Meredith D J
Cancer. 1980 Oct 15;46(8):1863-7. doi: 10.1002/1097-0142(19801015)46:8<1863::aid-cncr2820460826>3.0.co;2-1.
Malignant alteration in cystosarcoma phyllodes is uncommon and almost always confined to the stromal component. A rare case of recurring cystosarcoma is reported. In the first recurrence, lobular carcinoma in situ was present within the tumor and the second recurrence revealed tubular carcinoma within the cystosarcoma. Epithelial proliferation of various sorts is not uncommon in cystosarcomas but only two previous instances of infiltrating carcinoma have been observed within these tumors. The problem of mammary carcinoma coexisting with cystosarcoma is reviewed and comparisons are made with a closely related neoplasm, the fibroadenoma.
叶状囊肉瘤的恶性改变并不常见，几乎总是局限于间质成分。本文报告了一例罕见的复发性叶状囊肉瘤病例。首次复发时，肿瘤内存在小叶原位癌，第二次复发时，叶状囊肉瘤内出现了管状癌。各种上皮增生在叶状囊肉瘤中并不少见，但此前仅在这些肿瘤中观察到两例浸润性癌。本文回顾了乳腺癌与叶状囊肉瘤共存的问题，并与密切相关的肿瘤纤维腺瘤进行了比较。
