Jain Sunila, Kaur Ramneet, Agarwal Rajeev, Chopra Prem
Department of Pathology, Sir Ganga Ram Hospital, Rajinder Nagar, New Delhi, 110060 India.
Department of Pathology, Sir Ganga Ram Hospital, New Delhi, India.
Indian J Surg Oncol. 2014 Sep;5(3):186-8. doi: 10.1007/s13193-014-0338-z. Epub 2014 Jul 29.
Concomitant occurrence of phyllodes tumor with an in situ or invasive carcinoma in the breast is an uncommon phenomenon and has been reported sparingly. We describe a rare case of simultaneous bilateral intraductal and infiltrating duct carcinoma with coexisting fibroadenomas and phyllodes tumor. To the best of our knowledge, only 19 cases of invasive carcinoma with phyllodes tumor have been reported so far and lymph node metastases has been described only once. A 43 year-old woman presented with multiple bilateral breast lumps. Core biopsies revealed phyllodes tumor in the right breast and invasive duct carcinoma of the left breast. Simple mastectomy done for right breast showed foci of invasive carcinoma arising in phyllodes tumor. Metastasis was detected in the left axillary lymph nodes. This case is being reported to create awareness of this rare transformation, which has significant prognostic and therapeutic implications.
乳腺叶状肿瘤与原位癌或浸润性癌同时发生是一种罕见现象，相关报道较少。我们描述了一例罕见的双侧同时发生导管内癌和浸润性导管癌，并伴有纤维腺瘤和叶状肿瘤的病例。据我们所知，迄今为止仅报道了19例浸润性癌合并叶状肿瘤的病例，其中仅有1例描述有淋巴结转移。一名43岁女性因双侧乳腺多发肿块就诊。核心活检显示右乳腺为叶状肿瘤，左乳腺为浸润性导管癌。右侧乳腺单纯乳房切除术显示叶状肿瘤内出现浸润性癌灶。左侧腋窝淋巴结检测到转移。报道该病例是为了提高对这种罕见转变的认识，其具有重要的预后和治疗意义。
