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阴茎非霍奇金淋巴瘤2例的保守治疗:病例报告并文献复习

Conservative Therapy in Two Cases of Non-Hodgkin Lymphoma of the Penis: Case Reports With Review of the Literature.

作者信息

Delicato Giampaolo, Baffigo Giulio, Bianchi Daniele, Farullo Giuseppe, Signore Stefano, Tartaglia Edoardo, Corvese Francesco, Ferdinandi Vincenzo

机构信息

Deparment of Urology-Santo Eugenio Hospital Rome, Largo Umanesimo, 10 - 00144 Rome, Italy.

出版信息

World J Oncol. 2012 Feb;3(1):37-38. doi: 10.4021/wjon438w. Epub 2012 Feb 19.

Abstract

The malignant lymphomas rarely occur in the genito-urinary tract and particularly penis lymphomas are extremely uncommon. Frequently they do not have any specific symptoms and the diagnosis is delayed even in presence of a penis node. In our hospital we observed two patients affected by Non-Hodgkin Lymphoma (NHL), one of them with a primitive disease. Both cases were sexually active men who did not accept a radical surgery. A conservative polichemotherapy treatment by ciclophosphamide, vincristine and prednisone has been proposed and performed for both cases and a complete resolution of disease was demonstrated. At the same time we assessed the erectile function by the IIEF score, before and after treatments.

摘要

恶性淋巴瘤很少发生于泌尿生殖道,阴茎淋巴瘤尤其罕见。它们通常没有任何特异性症状,即使存在阴茎肿物,诊断也会延迟。在我们医院,我们观察到两名非霍奇金淋巴瘤(NHL)患者,其中一名为原发疾病。两例患者均为性活跃男性,他们均不接受根治性手术。我们为两例患者都提出并实施了环磷酰胺、长春新碱和泼尼松的保守联合化疗方案,结果显示疾病完全缓解。同时,我们在治疗前后通过国际勃起功能指数(IIEF)评分评估勃起功能。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8913/5649834/75c235d6b9cb/wjon-03-037-g001.jpg

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