Wortman J E, Lucas V S, Schuster E, Thiele D, Logue G L
Cancer. 1979 Nov;44(5):1588-91. doi: 10.1002/1097-0142(197911)44:5<1588::aid-cncr2820440508>3.0.co;2-x.
Three patients are described who either died suddenly or had severe, life-threatening arrhythmias during or immediately after doxorubicin administration. Since doxorubicin and daunorubicin administration is known to be associated with acute EKG abnormalities, the acute decompensation in these patients appeared to be caused by the administration of these agents. The importance of careful observation of patients receiving doxorubicin, because of the possibility of acute cardiac arrhythmias, is stressed.
本文描述了三名患者，他们在给予阿霉素期间或之后突然死亡，或出现严重的、危及生命的心律失常。由于已知给予阿霉素和柔红霉素与急性心电图异常有关，这些患者的急性失代偿似乎是由这些药物的给药引起的。强调了对接受阿霉素治疗的患者进行仔细观察的重要性，因为可能会出现急性心律失常。
