Mahta Ali, Vijayvergia Namrata, Bhavsar Tapan M, Ward Lawrence D
Department of Medicine, Temple University Hospital, USA.
Department of Neurology, Temple University Hospital, USA.
World J Oncol. 2012 Oct;3(5):243-246. doi: 10.4021/wjon571w. Epub 2012 Oct 28.
Herein, we discussed a case of an otherwise healthy man who presented with progressive gait imbalance and ataxia, found to have small cell lung cancer. Based upon our clinical findings and laboratory data, a diagnosis of paraneoplastic cerebellar degeneration was made. Paraneoplastic neurological syndromes (PNS) are relatively rare but diverse and always should be considered in differentials. A diagnostic algorithm along with appropriate work up is discussed here.
在此,我们讨论了一例原本健康的男性患者,他出现进行性步态失衡和共济失调,经检查发现患有小细胞肺癌。根据我们的临床发现和实验室数据,诊断为副肿瘤性小脑变性。副肿瘤性神经系统综合征(PNS)相对罕见但表现多样,在鉴别诊断时应始终予以考虑。本文讨论了一种诊断算法以及适当的检查方法。